ID   ISIA_NOSS1              Reviewed;         344 AA.
AC   Q8YQ35;
DT   07-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Iron stress-induced chlorophyll-binding protein;
DE   AltName: Full=CP43';
GN   Name=isiA; OrderedLocusNames=all4001;
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
CC   -!- FUNCTION: Functions as an antenna for photosystem I (PSI) under iron-
CC       limiting conditions, when phycobilisomes disappear. In the
CC       (PSI)3(Isi3)18 complex most of the harvested energy is probably used by
CC       PSI; in other PSI-containing supercomplexes a large part of the energy
CC       will probably not be used for light harvesting, but rather is
CC       dissipated to protect the organism from light damage.
CC       {ECO:0000250|UniProtKB:P15347}.
CC   -!- COFACTOR:
CC       Name=chlorophyll a; Xref=ChEBI:CHEBI:58416;
CC         Evidence={ECO:0000250|UniProtKB:P15347};
CC       Note=Chlorophyll a. {ECO:0000250|UniProtKB:P15347};
CC   -!- COFACTOR:
CC       Name=all-trans-beta-carotene; Xref=ChEBI:CHEBI:17579;
CC         Evidence={ECO:0000250|UniProtKB:P15347};
CC   -!- SUBUNIT: Under iron-starvation forms a complex with PSI trimers, where
CC       the trimer is surrounded by a ring composed of 18 IsiA subunits.
CC       {ECO:0000250|UniProtKB:P15347}.
CC   -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane
CC       {ECO:0000250|UniProtKB:P15347}; Multi-pass membrane protein
CC       {ECO:0000305}.
CC   -!- INDUCTION: By iron stress. {ECO:0000250|UniProtKB:P15347}.
CC   -!- SIMILARITY: Belongs to the PsbB/PsbC family. IsiA/Pcb subfamily.
CC       {ECO:0000305}.
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DR   EMBL; BA000019; BAB75700.1; -; Genomic_DNA.
DR   PIR; AB2306; AB2306.
DR   PIR; S42648; S42648.
DR   RefSeq; WP_010998141.1; NZ_RSCN01000023.1.
DR   AlphaFoldDB; Q8YQ35; -.
DR   SMR; Q8YQ35; -.
DR   STRING; 103690.17133136; -.
DR   EnsemblBacteria; BAB75700; BAB75700; BAB75700.
DR   KEGG; ana:all4001; -.
DR   eggNOG; ENOG502Z92X; Bacteria.
DR   OMA; KFHFEWN; -.
DR   OrthoDB; 417558at2; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0009522; C:photosystem I; IEA:UniProtKB-KW.
DR   GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016168; F:chlorophyll binding; IEA:UniProtKB-KW.
DR   GO; GO:0009767; P:photosynthetic electron transport chain; IEA:InterPro.
DR   InterPro; IPR000932; PS_antenna-like.
DR   InterPro; IPR036001; PS_II_antenna-like_sf.
DR   PANTHER; PTHR33180; PTHR33180; 2.
DR   Pfam; PF00421; PSII; 2.
DR   SUPFAM; SSF161077; SSF161077; 1.
PE   3: Inferred from homology;
KW   Chlorophyll; Chromophore; Membrane; Photosynthesis; Photosystem I;
KW   Reference proteome; Stress response; Thylakoid; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..344
FT                   /note="Iron stress-induced chlorophyll-binding protein"
FT                   /id="PRO_0000077556"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        89..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        138..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        203..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        240..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        303..323
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   344 AA;  37667 MW;  46EDD1E0F7D84A38 CRC64;
     MQTYDNPNIK YDWWAGNARF ANLSGLFIGA HVAQAALTTL WAGAFTWFEI SRYKPEIPMG
     EQGLILLPHL ATLGFGVGVS GQVVNTYPYF VIGALHLISS AVLGAGALFH TFKGPRNLKN
     TTGSARKFHF EWNDPKQLGL ILGHHLLFLG MAALLLVGKA MFWGGLYDAT TQVVRVVNHP
     TLNPFVIYGY QTHFASVNNL EDLVGGHIYV GLILIGGGIW HIVKEPLPWA KKLLIFSGEA
     ILSYSLGGIA LAGFVAAYFC AVNTLAYPVE FYGAPLELKF GVTPYFADTV KLADGGYSAR
     AWLANAHFFL AFFFLQGHLW HALRAIGVDF RQIEKSLNAI SSAE