ID   ISIA_SYNP6              Reviewed;         342 AA.
AC   Q5N675;
DT   07-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Iron stress-induced chlorophyll-binding protein;
DE   AltName: Full=CP43';
GN   Name=isiA; OrderedLocusNames=syc0002_c;
OS   Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis
OS   nidulans).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX   NCBI_TaxID=269084;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27144 / PCC 6301 / SAUG 1402/1;
RX   PubMed=17211581; DOI=10.1007/s11120-006-9122-4;
RA   Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M.,
RA   Kanehisa M., Omata T., Sugiura M., Sugita M.;
RT   "Complete nucleotide sequence of the freshwater unicellular cyanobacterium
RT   Synechococcus elongatus PCC 6301 chromosome: gene content and
RT   organization.";
RL   Photosyn. Res. 93:55-67(2007).
CC   -!- FUNCTION: Functions as an antenna for photosystem I (PSI) under iron-
CC       limiting conditions, when phycobilisomes disappear. In the
CC       (PSI)3(Isi3)18 complex most of the harvested energy is probably used by
CC       PSI; in other PSI-containing supercomplexes a large part of the energy
CC       will probably not be used for light harvesting, but rather is
CC       dissipated to protect the organism from light damage.
CC       {ECO:0000250|UniProtKB:P15347}.
CC   -!- COFACTOR:
CC       Name=chlorophyll a; Xref=ChEBI:CHEBI:58416;
CC         Evidence={ECO:0000250|UniProtKB:P15347};
CC       Note=Chlorophyll a. {ECO:0000250|UniProtKB:P15347};
CC   -!- COFACTOR:
CC       Name=all-trans-beta-carotene; Xref=ChEBI:CHEBI:17579;
CC         Evidence={ECO:0000250|UniProtKB:P15347};
CC   -!- SUBUNIT: Under iron-starvation forms a complex with PSI trimers, where
CC       the trimer is surrounded by a ring composed of 18 IsiA subunits.
CC       {ECO:0000250|UniProtKB:P15347}.
CC   -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane
CC       {ECO:0000250|UniProtKB:P15347}; Multi-pass membrane protein
CC       {ECO:0000305}.
CC   -!- INDUCTION: By iron stress. {ECO:0000250|UniProtKB:P15347}.
CC   -!- SIMILARITY: Belongs to the PsbB/PsbC family. IsiA/Pcb subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AP008231; BAD78192.1; -; Genomic_DNA.
DR   RefSeq; WP_011242315.1; NC_006576.1.
DR   AlphaFoldDB; Q5N675; -.
DR   SMR; Q5N675; -.
DR   STRING; 269084.syc0002_c; -.
DR   EnsemblBacteria; BAD78192; BAD78192; syc0002_c.
DR   KEGG; syc:syc0002_c; -.
DR   eggNOG; ENOG502Z92X; Bacteria.
DR   OMA; FGEYTEF; -.
DR   Proteomes; UP000001175; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0009522; C:photosystem I; IEA:UniProtKB-KW.
DR   GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016168; F:chlorophyll binding; IEA:UniProtKB-KW.
DR   GO; GO:0009767; P:photosynthetic electron transport chain; IEA:InterPro.
DR   InterPro; IPR000932; PS_antenna-like.
DR   InterPro; IPR036001; PS_II_antenna-like_sf.
DR   PANTHER; PTHR33180; PTHR33180; 1.
DR   Pfam; PF00421; PSII; 1.
DR   SUPFAM; SSF161077; SSF161077; 1.
PE   3: Inferred from homology;
KW   Chlorophyll; Chromophore; Membrane; Photosynthesis; Photosystem I;
KW   Stress response; Thylakoid; Transmembrane; Transmembrane helix.
FT   CHAIN           1..342
FT                   /note="Iron stress-induced chlorophyll-binding protein"
FT                   /id="PRO_0000077560"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        89..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        240..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        308..328
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   342 AA;  36976 MW;  ACE889338C0F44ED CRC64;
     MQTYNNPEVT YDWWAGNARF ANLSGLFIAA HVAQAALIMF WAGAFTLYEI SWLTADQSMG
     EQGLILLPHL ATLGLGVGDG GQVTDTYPLF VVGAVHLIAS AVLGAGALFH TFRAPSDLAA
     ASGAAKRFHF DWNDPKQLGL ILGHHLLFLG VGALLLVAKA TTWGGLYDAA SQTVRLVTEP
     TLNPAVIYGY QTHFASIDNL EDLVGGHVYV GVMLIAGGIW HILVPPFQWT KKVLIYSGEA
     ILSYSLGGIA LAGFVAAYFC AVNTLAYPVE FYGAPLEIKL GVTPYFADTV QLPFGAHTPR
     AWLSNAHFFL AFFCLQGHLW HALRAMGFDF RRVEKALSSV EA