ID   ISIA_THEVB              Reviewed;         358 AA.
AC   Q8DK20;
DT   07-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Iron stress-induced chlorophyll-binding protein;
DE   AltName: Full=CP43';
GN   Name=isiA; OrderedLocusNames=tlr1050;
OS   Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1).
OC   Bacteria; Cyanobacteria; Pseudanabaenales; Thermosynechococcaceae;
OC   Thermosynechococcus.
OX   NCBI_TaxID=197221;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIES-2133 / IAM M-273 / BP-1;
RX   PubMed=12240834; DOI=10.1093/dnares/9.4.123;
RA   Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S.,
RA   Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C.,
RA   Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takeuchi C., Yamada M., Tabata S.;
RT   "Complete genome structure of the thermophilic cyanobacterium
RT   Thermosynechococcus elongatus BP-1.";
RL   DNA Res. 9:123-130(2002).
CC   -!- FUNCTION: Functions as an antenna for photosystem I (PSI) under iron-
CC       limiting conditions, when phycobilisomes disappear. In the
CC       (PSI)3(Isi3)18 complex most of the harvested energy is probably used by
CC       PSI; in other PSI-containing supercomplexes a large part of the energy
CC       will probably not be used for light harvesting, but rather is
CC       dissipated to protect the organism from light damage.
CC       {ECO:0000250|UniProtKB:Q55274}.
CC   -!- COFACTOR:
CC       Name=chlorophyll a; Xref=ChEBI:CHEBI:58416;
CC         Evidence={ECO:0000250|UniProtKB:Q55274};
CC       Note=Chlorophyll a. {ECO:0000250|UniProtKB:Q55274};
CC   -!- COFACTOR:
CC       Name=all-trans-beta-carotene; Xref=ChEBI:CHEBI:17579;
CC         Evidence={ECO:0000250|UniProtKB:Q55274};
CC   -!- SUBUNIT: Under iron-starvation forms a complex with PSI trimers, where
CC       the trimer is surrounded by a ring composed of 18 IsiA subunits.
CC       {ECO:0000250|UniProtKB:Q55274}.
CC   -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane
CC       {ECO:0000250|UniProtKB:Q55274}; Multi-pass membrane protein
CC       {ECO:0000305}.
CC   -!- INDUCTION: By iron stress. {ECO:0000250|UniProtKB:Q55274}.
CC   -!- SIMILARITY: Belongs to the PsbB/PsbC family. IsiA/Pcb subfamily.
CC       {ECO:0000305}.
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DR   EMBL; BA000039; BAC08603.1; -; Genomic_DNA.
DR   RefSeq; NP_681841.1; NC_004113.1.
DR   AlphaFoldDB; Q8DK20; -.
DR   SMR; Q8DK20; -.
DR   STRING; 197221.22294774; -.
DR   EnsemblBacteria; BAC08603; BAC08603; BAC08603.
DR   KEGG; tel:tlr1050; -.
DR   PATRIC; fig|197221.4.peg.1103; -.
DR   eggNOG; ENOG502Z92X; Bacteria.
DR   OMA; KFHFEWN; -.
DR   OrthoDB; 417558at2; -.
DR   Proteomes; UP000000440; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0009522; C:photosystem I; IEA:UniProtKB-KW.
DR   GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016168; F:chlorophyll binding; IEA:UniProtKB-KW.
DR   GO; GO:0009767; P:photosynthetic electron transport chain; IEA:InterPro.
DR   InterPro; IPR000932; PS_antenna-like.
DR   InterPro; IPR036001; PS_II_antenna-like_sf.
DR   PANTHER; PTHR33180; PTHR33180; 2.
DR   Pfam; PF00421; PSII; 1.
DR   SUPFAM; SSF161077; SSF161077; 1.
PE   3: Inferred from homology;
KW   Chlorophyll; Chromophore; Membrane; Photosynthesis; Photosystem I;
KW   Reference proteome; Stress response; Thylakoid; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..358
FT                   /note="Iron stress-induced chlorophyll-binding protein"
FT                   /id="PRO_0000077558"
FT   TRANSMEM        40..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        219..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        255..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        318..338
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   358 AA;  39252 MW;  3DA71B09CFD41320 CRC64;
     MAIASESPTT VTSAGLQTYG QTNVKYDWWA GNARFVNLSG LFIAAHVAQA ALSVFWAGAF
     TLYEISQYKP DLPMGEQGLI LLPHLATLGF GIGEGGKVVD LYPYFVIGAV HLISSAVLGA
     GALFHTFRAP HDLSTATGRA RRFHFRWDDP KQLGIILGHH LLFLGFGALL LVLKATIWGG
     LYDANLQTVR LITQPTLDPF VIYGYQTHFA SINSLEDLVG GHIYIAILLI AGGIWHILVP
     PLTWARKLLM FNAEAILSYS LGGIALAGFV AAYFCAVNTL AYPVEFYGPP LEVKLGIAPY
     FADTIELPLG QHTSRAWLAN AHFFLAFFFL QGHLWHALRA MGFNFKQLET FLNPAIEN