ID   ISOC2_BOVIN             Reviewed;         204 AA.
AC   Q32KX0;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Isochorismatase domain-containing protein 2;
GN   Name=ISOC2;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Interacts with CDKN2A. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC       Note=Localizes to the nucleus in the presence of CDKN2A. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the isochorismatase family. {ECO:0000305}.
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DR   EMBL; BC109878; AAI09879.1; -; mRNA.
DR   RefSeq; NP_001033212.1; NM_001038123.2.
DR   AlphaFoldDB; Q32KX0; -.
DR   SMR; Q32KX0; -.
DR   STRING; 9913.ENSBTAP00000021209; -.
DR   PaxDb; Q32KX0; -.
DR   PRIDE; Q32KX0; -.
DR   GeneID; 516212; -.
DR   KEGG; bta:516212; -.
DR   CTD; 79763; -.
DR   eggNOG; KOG4044; Eukaryota.
DR   InParanoid; Q32KX0; -.
DR   OrthoDB; 1100720at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.850; -; 1.
DR   InterPro; IPR040318; ISOC2.
DR   InterPro; IPR000868; Isochorismatase-like.
DR   InterPro; IPR036380; Isochorismatase-like_sf.
DR   PANTHER; PTHR14119:SF4; PTHR14119:SF4; 1.
DR   Pfam; PF00857; Isochorismatase; 1.
DR   SUPFAM; SSF52499; SSF52499; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..204
FT                   /note="Isochorismatase domain-containing protein 2"
FT                   /id="PRO_0000268670"
SQ   SEQUENCE   204 AA;  22420 MW;  C06EA50F52935EBB CRC64;
     MAAARPALGR VLPGSSMLFL CDMQEKFRHV VYFRQIVSMA ARMLKVARLL SVPTVLTEQY
     PQGLGPTVPE LGAQGLQPYS KTCFSMVPAV QQELDARPQL RSVLLCGVET QACILQTALD
     LLDRGLQVHV VVDACTSRSQ VDRLVALSRL RQSGAFLSTS EGLIFQLVGD ATHPQFKEIQ
     KLVKEPSPDS GLLGLFQDQN PLFR