ID   ISOC2_MACFA             Reviewed;         205 AA.
AC   Q4R826;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Isochorismatase domain-containing protein 2;
GN   Name=ISOC2; ORFNames=QtsA-13690;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Interacts with CDKN2A. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC       Note=Localizes to the nucleus in the presence of CDKN2A. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the isochorismatase family. {ECO:0000305}.
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DR   EMBL; AB168635; BAE00746.1; -; mRNA.
DR   AlphaFoldDB; Q4R826; -.
DR   SMR; Q4R826; -.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.850; -; 1.
DR   InterPro; IPR040318; ISOC2.
DR   InterPro; IPR000868; Isochorismatase-like.
DR   InterPro; IPR036380; Isochorismatase-like_sf.
DR   PANTHER; PTHR14119:SF4; PTHR14119:SF4; 1.
DR   Pfam; PF00857; Isochorismatase; 1.
DR   SUPFAM; SSF52499; SSF52499; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..205
FT                   /note="Isochorismatase domain-containing protein 2"
FT                   /id="PRO_0000268672"
SQ   SEQUENCE   205 AA;  22341 MW;  F98F94B6AB81BAD1 CRC64;
     MAAARPILGR VLPGSSILFL CDMQEKFRHN IAYFPQIVSV AARMLRVARL LEVPVLLTEQ
     YPQGLGPTVP ELGAEGLQPL TKTCFSMVPA LQQELDSRPQ LRSVLLCGIE AQACILNTTL
     DLLDRGLQVH VVVDACSSRS QVDRLVALAR MRQSGAFLST SEGLILQLVG DAAHPQFKEI
     QKLIKEPAPD SGLLGLFQGQ NPLLH