ID   ISOLC_AGEAP             Reviewed;          18 AA.
AC   Q9TWH3;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 24.
DE   RecName: Full=Venom peptide isomerase light chain;
OS   Agelenopsis aperta (North American funnel-web spider) (Agelenopsis
OS   gertschi).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC   Araneomorphae; Entelegynae; Agelenidae; Agelenopsis.
OX   NCBI_TaxID=6908;
RN   [1]
RP   PROTEIN SEQUENCE, FUNCTION, SUBUNIT, SUBCELLULAR LOCATION, TISSUE
RP   SPECIFICITY, AND DISULFIDE BOND.
RC   TISSUE=Venom;
RX   PubMed=7622482; DOI=10.1074/jbc.270.28.16719;
RA   Shikata Y., Watanabe T., Teramoto T., Inoue A., Kawakami Y., Nishizawa Y.,
RA   Katayama K., Kuwada M.;
RT   "Isolation and characterization of a peptide isomerase from funnel web
RT   spider venom.";
RL   J. Biol. Chem. 270:16719-16723(1995).
CC   -!- FUNCTION: Peptide isomerase that inverts the chirality at the Ser-81 of
CC       omega-Aga IVB. Acts cofactor-independently.
CC       {ECO:0000269|PubMed:7622482}.
CC   -!- SUBUNIT: Heterodimer with venom peptide isomerase heavy chain;
CC       disulfide-linked. {ECO:0000269|PubMed:7622482}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:7622482}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC       {ECO:0000269|PubMed:7622482}.
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DR   AlphaFoldDB; Q9TWH3; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Isomerase; Secreted.
FT   CHAIN           1..18
FT                   /note="Venom peptide isomerase light chain"
FT                   /id="PRO_0000404524"
FT   DISULFID        9
FT                   /note="Interchain (with C-116 in venom peptide isomerase
FT                   heavy chain)"
FT                   /evidence="ECO:0000269|PubMed:7622482"
SQ   SEQUENCE   18 AA;  1927 MW;  F4FBA22332E97774 CRC64;
     VEVATVKNCG KKLLATPR