ID   ISP1_GALME              Reviewed;          50 AA.
AC   P81905;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 34.
DE   RecName: Full=Inducible serine protease inhibitor 1;
DE            Short=ISPI-1;
DE   Flags: Fragment;
OS   Galleria mellonella (Greater wax moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Pyraloidea;
OC   Pyralidae; Galleriinae; Galleria.
OX   NCBI_TaxID=7137;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Hemolymph;
RX   PubMed=10727944; DOI=10.1046/j.1432-1327.2000.01207.x;
RA   Froebius A.C., Kanost M.R., Goetz P., Vilcinskas A.;
RT   "Isolation and characterization of novel inducible serine protease
RT   inhibitors from larval hemolymph of the greater wax moth Galleria
RT   mellonella.";
RL   Eur. J. Biochem. 267:2046-2053(2000).
CC   -!- FUNCTION: Inhibits trypsin and the toxin protease PR2 of M.anisopliae.
CC       Does not inhibit chymotrypsin, subtilisin Carlsberg, proteinase K,
CC       porcine pancreatic elastase and the toxin protease PR1 of M.anisopliae.
CC   -!- DEVELOPMENTAL STAGE: Last instar larvae.
CC   -!- INDUCTION: By infection.
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DR   MEROPS; I83.002; -.
DR   Proteomes; UP000504614; Unplaced.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   InterPro; IPR021066; FPI1.
DR   Pfam; PF12190; amfpi-1; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Protease inhibitor; Reference proteome;
KW   Serine protease inhibitor.
FT   CHAIN           1..>50
FT                   /note="Inducible serine protease inhibitor 1"
FT                   /id="PRO_0000084258"
FT   NON_TER         50
SQ   SEQUENCE   50 AA;  5379 MW;  AD67E6C9D8BC9254 CRC64;
     DLVXGTNFXK NNPXSTRVAA NSXRSPSVYR QXXXXHAKKA AXPPAVVTLL