ISP3_GALME
ID ISP3_GALME Reviewed; 41 AA.
AC P81907;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 33.
DE RecName: Full=Inducible serine protease inhibitor 3;
DE Short=ISPI-3;
DE Flags: Fragment;
OS Galleria mellonella (Greater wax moth).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Pyraloidea;
OC Pyralidae; Galleriinae; Galleria.
OX NCBI_TaxID=7137;
RN [1]
RP PROTEIN SEQUENCE.
RC TISSUE=Hemolymph;
RX PubMed=10727944; DOI=10.1046/j.1432-1327.2000.01207.x;
RA Froebius A.C., Kanost M.R., Goetz P., Vilcinskas A.;
RT "Isolation and characterization of novel inducible serine protease
RT inhibitors from larval hemolymph of the greater wax moth Galleria
RT mellonella.";
RL Eur. J. Biochem. 267:2046-2053(2000).
CC -!- FUNCTION: Inhibits trypsin and the toxin proteases PR1 and PR2 of
CC M.anisopliae. Does not inhibit chymotrypsin, subtilisin Carlsberg,
CC proteinase K and porcine pancreatic elastase.
CC -!- DEVELOPMENTAL STAGE: Last instar larvae.
CC -!- INDUCTION: By infection.
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DR Proteomes; UP000504614; Unplaced.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Protease inhibitor; Reference proteome;
KW Serine protease inhibitor.
FT CHAIN 1..>41
FT /note="Inducible serine protease inhibitor 3"
FT /id="PRO_0000084259"
FT NON_TER 41
SQ SEQUENCE 41 AA; 4541 MW; C919A4AE1959D723 CRC64;
NKTNLKQLKA EAARKKAXMQ DMXTSVKVEP LXAXXNGAXR M