ID   1104L_ASFPP             Reviewed;         124 AA.
AC   A9JLI5;
DT   23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 17.
DE   RecName: Full=Protein MGF 110-4L;
DE   Flags: Precursor;
GN   Name=MGF 110-4L {ECO:0000312|EMBL:CAN10358.1};
OS   African swine fever virus (isolate Pig/Portugal/OURT88/1988) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=443878;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OURT 88/3 {ECO:0000312|EMBL:CAN10358.1};
RX   PubMed=18198370; DOI=10.1099/vir.0.83343-0;
RA   Chapman D.A.G., Tcherepanov V., Upton C., Dixon L.K.;
RT   "Comparison of the genome sequences of non-pathogenic and pathogenic
RT   African swine fever virus isolates.";
RL   J. Gen. Virol. 89:397-408(2008).
RN   [2]
RP   SIGNAL SEQUENCE CLEAVAGE SITE.
RX   PubMed=30279544; DOI=10.1038/s41598-018-32985-z;
RA   Kessler C., Forth J.H., Keil G.M., Mettenleiter T.C., Blome S., Karger A.;
RT   "The intracellular proteome of African swine fever virus.";
RL   Sci. Rep. 8:14714-14714(2018).
CC   -!- FUNCTION: Causes the redistribution of lumenal ER protein to an
CC       enlarged ERGIC compartment. {ECO:0000250|UniProtKB:P18558}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:P18558}. Host
CC       endoplasmic reticulum-Golgi intermediate compartment
CC       {ECO:0000250|UniProtKB:P18558}.
CC   -!- SIMILARITY: Belongs to the asfivirus MGF 110 family. {ECO:0000305}.
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DR   EMBL; AM712240; CAN10358.1; -; Genomic_DNA.
DR   Proteomes; UP000108903; Genome.
DR   GO; GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.
DR   InterPro; IPR004848; ASFV_fam_110.
DR   Pfam; PF01639; v110; 1.
PE   1: Evidence at protein level;
KW   Early protein; Glycoprotein; Signal; Virion.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000269|PubMed:30279544"
FT   CHAIN           29..124
FT                   /note="Protein MGF 110-4L"
FT                   /id="PRO_0000454842"
FT   MOTIF           121..124
FT                   /note="Prevents secretion from ER"
FT                   /evidence="ECO:0000250|UniProtKB:P18558"
FT   CARBOHYD        64
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   124 AA;  14452 MW;  E945A4A4743465DA CRC64;
     MLVIFLGILG LLANQVLGLP TQAEGHLRST DNPPQEELGY WCTYMESCKF CWECEHGICK
     NKVNRSMPWI IENSYLTSCE VSRWYNQCTY DEGNGHYHVM DCSNPVPHNR PHRLGRKIYE
     KEDL