ID   ITGBL_RAT               Reviewed;         494 AA.
AC   Q5PQQ8;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Integrin beta-like protein 1;
DE   Flags: Precursor;
GN   Name=Itgbl1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- DOMAIN: Contains ten tandem EGF-like repeats strikingly similar to
CC       those found in the cysteine rich 'stalk-like' structure of integrin
CC       beta-subunits.
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DR   EMBL; BC087076; AAH87076.1; -; mRNA.
DR   RefSeq; NP_001017505.1; NM_001017505.1.
DR   AlphaFoldDB; Q5PQQ8; -.
DR   STRING; 10116.ENSRNOP00000006264; -.
DR   GlyGen; Q5PQQ8; 1 site.
DR   PaxDb; Q5PQQ8; -.
DR   Ensembl; ENSRNOT00000006264; ENSRNOP00000006264; ENSRNOG00000004516.
DR   GeneID; 498564; -.
DR   KEGG; rno:498564; -.
DR   UCSC; RGD:1560635; rat.
DR   CTD; 9358; -.
DR   RGD; 1560635; Itgbl1.
DR   eggNOG; KOG1226; Eukaryota.
DR   GeneTree; ENSGT00980000198528; -.
DR   HOGENOM; CLU_043045_0_0_1; -.
DR   InParanoid; Q5PQQ8; -.
DR   OMA; CGNDCKK; -.
DR   OrthoDB; 18592at2759; -.
DR   PhylomeDB; Q5PQQ8; -.
DR   TreeFam; TF332636; -.
DR   PRO; PR:Q5PQQ8; -.
DR   Proteomes; UP000002494; Chromosome 15.
DR   Bgee; ENSRNOG00000004516; Expressed in quadriceps femoris and 20 other tissues.
DR   Genevisible; Q5PQQ8; RN.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005925; C:focal adhesion; IBA:GO_Central.
DR   GO; GO:0005178; F:integrin binding; IBA:GO_Central.
DR   GO; GO:0033627; P:cell adhesion mediated by integrin; IBA:GO_Central.
DR   GO; GO:0016477; P:cell migration; IBA:GO_Central.
DR   GO; GO:0007160; P:cell-matrix adhesion; IBA:GO_Central.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IBA:GO_Central.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR013111; EGF_extracell.
DR   InterPro; IPR027070; Integrin_b-like_p1.
DR   InterPro; IPR015812; Integrin_bsu.
DR   PANTHER; PTHR10082; PTHR10082; 1.
DR   PANTHER; PTHR10082:SF3; PTHR10082:SF3; 1.
DR   Pfam; PF07974; EGF_2; 4.
DR   SMART; SM00181; EGF; 6.
DR   PROSITE; PS00022; EGF_1; 5.
DR   PROSITE; PS01186; EGF_2; 5.
DR   PROSITE; PS00243; INTEGRIN_BETA; 9.
PE   2: Evidence at transcript level;
KW   EGF-like domain; Glycoprotein; Reference proteome; Repeat; Secreted;
KW   Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..494
FT                   /note="Integrin beta-like protein 1"
FT                   /id="PRO_0000323024"
FT   REPEAT          51..95
FT                   /note="I"
FT   REPEAT          96..142
FT                   /note="II"
FT   REPEAT          143..184
FT                   /note="III"
FT   REPEAT          185..230
FT                   /note="IV"
FT   REPEAT          231..275
FT                   /note="V"
FT   REPEAT          276..326
FT                   /note="VI"
FT   REPEAT          327..367
FT                   /note="VII"
FT   REPEAT          368..414
FT                   /note="VIII"
FT   REPEAT          415..454
FT                   /note="IX"
FT   REPEAT          455..494
FT                   /note="X"
FT   REGION          51..494
FT                   /note="Cysteine-rich tandem repeats"
FT   CARBOHYD        405
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   494 AA;  53904 MW;  8A60A8CA4FADD366 CRC64;
     MHPPGFKNFL LLVSSLFFIG LSAAPQSFSP SLRSLSGAPC RLSRAESERR CRAPGQPPGS
     ALCHDRGRCE CGVCICHVTE PGTYFGPLCE CHDWVCETYD GKTCAGHGTC DCGKCKCDVG
     WSGEACQYPT KCDLTKKISN QMCKNSQDVI CSNAGTCHCG RCKCDNSDGH GLIYGKFCEC
     DDRECIDDET EEICGGHGKC YCGNCYCEAG WHGDKCEFQC DITPWESKRR CTSPDGKVCS
     NRGTCVCGEC SCHDVDPTGD WGDIHGDTCE CDERDCRAVY DRYSDDFCSG HGQCNCGRCD
     CRAGWYGKKC EHPKNCPLSA EESTRKCQGS SDLPCSGRGR CECGRCTCYP PGDSRVYGKT
     CECDDRRCED LDGVVCGGRG TCSCGRCVCE KGWFGKLCQH PRKCNMTEEQ SRSLCESADG
     TLCSGKGSCH CGKCICSGEE WYISGEFCDC DDRDCDKHDG LICTGNGICS CGNCECWDGW
     NGNACEIWLG TEYP