ID   ITGBL_XENLA             Reviewed;         488 AA.
AC   Q5M9B3; Q7ZTJ2;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Integrin beta-like protein 1;
DE   Flags: Precursor;
GN   Name=itgbl1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo, and Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- DOMAIN: Contains ten tandem EGF-like repeats strikingly similar to
CC       those found in the cysteine rich 'stalk-like' structure of integrin
CC       beta-subunits.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH46744.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BC087328; AAH87328.1; -; mRNA.
DR   EMBL; BC046744; AAH46744.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001084310.1; NM_001090841.1.
DR   AlphaFoldDB; Q5M9B3; -.
DR   DNASU; 399430; -.
DR   GeneID; 399430; -.
DR   KEGG; xla:399430; -.
DR   CTD; 399430; -.
DR   Xenbase; XB-GENE-989421; itgbl1.L.
DR   OrthoDB; 18592at2759; -.
DR   Proteomes; UP000186698; Chromosome 2L.
DR   Bgee; 399430; Expressed in internal ear and 14 other tissues.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR013111; EGF_extracell.
DR   InterPro; IPR027070; Integrin_b-like_p1.
DR   InterPro; IPR015812; Integrin_bsu.
DR   PANTHER; PTHR10082; PTHR10082; 1.
DR   PANTHER; PTHR10082:SF3; PTHR10082:SF3; 1.
DR   Pfam; PF07974; EGF_2; 4.
DR   SMART; SM00181; EGF; 5.
DR   PROSITE; PS00022; EGF_1; 5.
DR   PROSITE; PS01186; EGF_2; 5.
DR   PROSITE; PS00243; INTEGRIN_BETA; 9.
PE   2: Evidence at transcript level;
KW   EGF-like domain; Glycoprotein; Reference proteome; Repeat; Secreted;
KW   Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..488
FT                   /note="Integrin beta-like protein 1"
FT                   /id="PRO_0000323025"
FT   REPEAT          49..89
FT                   /note="I"
FT   REPEAT          90..136
FT                   /note="II"
FT   REPEAT          137..178
FT                   /note="III"
FT   REPEAT          179..224
FT                   /note="IV"
FT   REPEAT          225..269
FT                   /note="V"
FT   REPEAT          270..320
FT                   /note="VI"
FT   REPEAT          321..361
FT                   /note="VII"
FT   REPEAT          362..408
FT                   /note="VIII"
FT   REPEAT          409..448
FT                   /note="IX"
FT   REPEAT          449..488
FT                   /note="X"
FT   REGION          49..488
FT                   /note="Cysteine-rich tandem repeats"
FT   CARBOHYD        399
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   488 AA;  53129 MW;  0AA013CE6ADD1326 CRC64;
     MHAGAFINFV WALSLVSLLA AVPPSPSFSL KNLPSTACRL PPAVSEKRCR TPDGSICSGR
     GSCDCGICLC EVKEAGKYYG PLCECHDWVC HTYDGQVCAG HGQCDCGVCK CDVGWSGEAC
     QYPTTCDLTR KKSNEMCKNS QAVICSNAGT CQCGRCKCEN SDNSGLIYGK YCECDDTECF
     DDETQEICGG HGKCYCGNCY CEAGWHGDKC EFQCDITPWE IKKRCTSPDG KICSNRGTCV
     CGECTCHDVD PTGDWGDIHG DTCECDERNC KSVYDRYSDD FCSGHGQCNC GRCDCKDGWT
     GRKCEHPRAC ALSIEESKKK CQGSASQPCS GRGKCECGQC TCFPPGDSKV YGKNCECDDR
     QCEDLEGKIC GEHGTCSCGR CICEAGWFGK LCQHERKCNM TEEESKSQCE SDDGILCSGK
     GSCHCGKCIC SPQEWYVSGE FCECDDRDCD KHDGLICTGN GICNCGNCEC WEGWNGNACE
     IWLGSEYP