ID   ITGL_AGRIP              Reviewed;         217 AA.
AC   C0HKU1;
DT   23-MAY-2018, integrated into UniProtKB/Swiss-Prot.
DT   23-MAY-2018, sequence version 1.
DT   25-MAY-2022, entry version 7.
DE   RecName: Full=ITG-like peptide {ECO:0000303|PubMed:29466015};
DE   Flags: Precursor;
OS   Agrotis ipsilon (Black cutworm moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC   Noctuidae; Noctuinae; Noctuini; Agrotis.
OX   NCBI_TaxID=56364;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 211-217, TISSUE
RP   SPECIFICITY, MASS SPECTROMETRY, AND IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=29466015; DOI=10.1021/acs.jproteome.7b00779;
RA   Diesner M., Gallot A., Binz H., Gaertner C., Vitecek S., Kahnt J.,
RA   Schachtner J., Jacquin-Joly E., Gadenne C.;
RT   "Mating-induced differential peptidomics of neuropeptides and protein
RT   hormones in Agrotis ipsilon moths.";
RL   J. Proteome Res. 17:1397-1414(2018).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: ITG-like peptide: Expressed in corpora cardiaca
CC       (CC), corpora allata (CA), antennal lobe (AL) and gnathal ganglion
CC       (GNG) (at protein level). Expression in AL detected in all animals,
CC       expression in GNG detected in most animals and in CA and CC detected in
CC       few animals (at protein level). {ECO:0000269|PubMed:29466015}.
CC   -!- MASS SPECTROMETRY: Mass=857.46; Mass_error=0.01; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:29466015};
CC   -!- CAUTION: Further mature peptides might exist. {ECO:0000305}.
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DR   AlphaFoldDB; C0HKU1; -.
DR   SMR; C0HKU1; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Cleavage on pair of basic residues; Direct protein sequencing;
KW   Neuropeptide; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   PROPEP          22..208
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000444174"
FT   PEPTIDE         211..217
FT                   /note="ITG-like peptide"
FT                   /evidence="ECO:0000269|PubMed:29466015"
FT                   /id="PRO_0000444175"
SQ   SEQUENCE   217 AA;  24019 MW;  5C3ADD5B1EA53792 CRC64;
     MHRTMAVTAV LVLSAAGAAH AWGGLFNRFS SDMLANLGYG RSPYRHYPYG QEPEEVYAEA
     LEGNRLDDVI DEPGHCYSAP CTTNGDCCRG LLCLDTEDGG RCLPAFAGRK LGEICNRENQ
     CDAGLVCEEV VPGEMHVCRP PTAGRKQYNE DCNSSSECDV TRGLCCIMQR RHRQKPRKSC
     GYFKEPLVCI GPVATDQIRE FVQHTAGEKR IGVYRLH