ID   ITP_PSHV1               Reviewed;         970 AA.
AC   Q6UDJ4;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   23-FEB-2022, entry version 47.
DE   RecName: Full=Inner tegument protein {ECO:0000255|HAMAP-Rule:MF_04043};
GN   Name=UL37;
OS   Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997) (PsHV-1)
OS   (Pacheco's disease virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Iltovirus.
OX   NCBI_TaxID=670426;
OH   NCBI_TaxID=152276; Amazona oratrix (yellow-headed parrot).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16873243; DOI=10.1128/jvi.00134-06;
RA   Thureen D.R., Keeler C.L. Jr.;
RT   "Psittacid herpesvirus 1 and infectious laryngotracheitis virus:
RT   Comparative genome sequence analysis of two avian alphaherpesviruses.";
RL   J. Virol. 80:7863-7872(2006).
CC   -!- FUNCTION: Plays an essential role in cytoplasmic secondary envelopment
CC       during viral egress. Interacts with the capsid via the large tegument
CC       protein/LTP and participates in its transport to the host trans-Golgi
CC       network (TGN) where secondary envelopment occurs. Modulates
CC       tegumentation and capsid accumulation at the viral assembly complex.
CC       {ECO:0000255|HAMAP-Rule:MF_04043}.
CC   -!- SUBUNIT: Interacts (via C-terminus) with the large tegument protein/LTP
CC       (via N-terminus). {ECO:0000255|HAMAP-Rule:MF_04043}.
CC   -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000255|HAMAP-
CC       Rule:MF_04043}. Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04043}. Host
CC       nucleus {ECO:0000255|HAMAP-Rule:MF_04043}. Host Golgi apparatus, host
CC       trans-Golgi network {ECO:0000255|HAMAP-Rule:MF_04043}.
CC   -!- SIMILARITY: Belongs to the herpesviridae inner tegument protein family.
CC       {ECO:0000255|HAMAP-Rule:MF_04043}.
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DR   EMBL; AY372243; AAQ73716.1; -; Genomic_DNA.
DR   RefSeq; NP_944410.1; NC_005264.1.
DR   SMR; Q6UDJ4; -.
DR   GeneID; 2656974; -.
DR   KEGG; vg:2656974; -.
DR   Proteomes; UP000006840; Genome.
DR   GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   GO; GO:0042802; F:identical protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0039701; P:microtubule-dependent intracellular transport of viral material towards cell periphery; IEA:UniProtKB-UniRule.
DR   GO; GO:0019068; P:virion assembly; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_04043; HSV_ITP; 1.
DR   InterPro; IPR034738; HSV_ITP.
PE   3: Inferred from homology;
KW   Host cytoplasm; Host Golgi apparatus; Host nucleus; Reference proteome;
KW   Virion; Virion tegument.
FT   CHAIN           1..970
FT                   /note="Inner tegument protein"
FT                   /id="PRO_0000406852"
FT   REGION          476..970
FT                   /note="Interaction with large tegument protein"
FT                   /evidence="ECO:0000250|UniProtKB:P10221"
SQ   SEQUENCE   970 AA;  105254 MW;  F4F6A41C65201557 CRC64;
     MAPKSACKNA LAQLAAELSS ASKRDTSSGS TRNSAPELTS LLADLLLSRD DVPLEDLEAT
     TARSHLAKGV FAACKLVPFP VAEVAVRLAV RAIMRRVVVP WQAGENFSMI QRVREAFLRL
     VDDFDNASKT ELNAPFTQCS EYKDLIGGWL TQFGNAVVLT MSEQQLLDDA GSVLNPPEVL
     APLVERYPLL IDHVMVQEGM DYLGGKLQSL VAYHALLRCA TRPHENGKVP VLAALTMVAE
     YFDPETKPAY RKVPQKAVAA FDLNLTDEVV SSLVYDQAAA PVVQSEQPVL PQSESLLFTE
     VVRTRNMLAL VQPSATWEGS GAALRNAAGD AKRRQQQAAR GAGMAWRCGV DALFSVPMEH
     VAMNVPAVMQ MLHEPPTDIP AEYERALSLY ATDTIDAIAK FPDLAASSGT EAVIRSLALR
     GFTKTNCERY LFAAEAFLEP QAPGTPLHDF YAAVIYASVV GLAAHSLYAY NQHTIFYPEK
     YSRVLKKTVE AHAYLLDMMG LAISDALISL RAFAPKPPHQ AFRTVRDTLA AVVDSVETGA
     EEFSDLIVSD YVQRLTADFY GGIHENEQWL SERDAAIRQR MEIAAAGRRE TDSAGRRPGL
     GFHELAALVQ GLQIGGKEPK AVVEYATAPA GAASAGATFS ALFAAAIVRD VMEGAAAIPF
     EADALARLNK ALSWLRDFGL SWNMPDGSHY RRRVIALQAA IHPFVTGKIG VDAVTVKQAR
     ALETAMGDLY AACEYSFQAL PPPYVGGLRK AAAPSRQHSP LLAQAYTNAA MGDLGVLTKT
     LAKSAEEISK TVRDMVSRLL SARDLFSRRA TASDKNAVTI DAAGPGGTVL GTWEDESVMS
     GLWKTVNFTE AAIRNTERAV RELEATKRET QDLEESYWQL ASGRDGAGNA AQPSESLYQQ
     VAAELVEIAD ARNAVVVRAR SLYRAIAGTG LKRIRTFVKA WRLFLKAERS LAKQVVQQQD
     LIDALDPSRS