ID   IVBL_BUNMU              Reviewed;          28 AA.
AC   Q9PTA2;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Beta-bungarotoxin B chain-like;
DE            Short=BL1;
DE   Flags: Precursor; Fragment;
OS   Bungarus multicinctus (Many-banded krait).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Elapidae; Bungarinae; Bungarus.
OX   NCBI_TaxID=8616;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Liver;
RX   PubMed=10903499; DOI=10.1046/j.1432-1327.2000.01518.x;
RA   Wu P.-F., Chang L.-S.;
RT   "Genetic organization of A chain and B chain of beta-bungarotoxin from
RT   Taiwan banded krait (Bungarus multicinctus). A chain genes and B chain
RT   genes do not share a common origin.";
RL   Eur. J. Biochem. 267:4668-4675(2000).
CC   -!- FUNCTION: Beta-1-bungarotoxin is a presynaptic neurotoxin of the venom.
CC       The B chain is homologous to venom basic protease inhibitors but has no
CC       protease inhibitor activity and blocks voltage-gated potassium channels
CC       (Kv) (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Heterodimer; disulfide-linked. The A chains have phospholipase
CC       A2 activity and the B chains show homology with the basic protease
CC       inhibitors (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
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DR   EMBL; AJ251225; CAB62514.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9PTA2; -.
DR   SMR; Q9PTA2; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0015459; F:potassium channel regulator activity; IEA:UniProtKB-KW.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Disulfide bond; Ion channel impairing toxin; Neurotoxin;
KW   Potassium channel impairing toxin; Presynaptic neurotoxin; Secreted;
KW   Signal; Toxin.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000250"
FT   CHAIN           25..>28
FT                   /note="Beta-bungarotoxin B chain-like"
FT                   /id="PRO_5000065750"
FT   NON_TER         28
SQ   SEQUENCE   28 AA;  2925 MW;  9FE294B890BCCBD4 CRC64;
     MSSGGLLLLL GLLTLCAELT PVSSKDRH