ID   IWS1_CAEBR              Reviewed;         497 AA.
AC   Q61MR2; A8X6E8;
DT   10-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   22-SEP-2009, sequence version 3.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=IWS1-like protein;
GN   ORFNames=CBG08373 {ECO:0000312|WormBase:CBG08373};
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00649}.
CC   -!- SIMILARITY: Belongs to the IWS1 family. {ECO:0000305}.
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DR   EMBL; HE601100; CAP28209.2; -; Genomic_DNA.
DR   AlphaFoldDB; Q61MR2; -.
DR   SMR; Q61MR2; -.
DR   STRING; 6238.CBG08373; -.
DR   EnsemblMetazoa; CBG08373.1; CBG08373.1; WBGene00030176.
DR   WormBase; CBG08373; CBP32781; WBGene00030176; -.
DR   eggNOG; KOG1793; Eukaryota.
DR   HOGENOM; CLU_040584_1_0_1; -.
DR   InParanoid; Q61MR2; -.
DR   OMA; EDMRRYD; -.
DR   OrthoDB; 1461546at2759; -.
DR   Proteomes; UP000008549; Chromosome IV.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IBA:GO_Central.
DR   Gene3D; 1.20.930.10; -; 1.
DR   InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR   InterPro; IPR017923; TFIIS_N.
DR   Pfam; PF08711; Med26; 1.
DR   PROSITE; PS51319; TFIIS_N; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..497
FT                   /note="IWS1-like protein"
FT                   /id="PRO_0000083351"
FT   DOMAIN          281..361
FT                   /note="TFIIS N-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00649"
FT   REGION          1..191
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          369..433
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..22
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        56..75
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        76..91
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        103..191
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        369..415
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   497 AA;  56062 MW;  E649196671FBB909 CRC64;
     MSDHEGASPA SSAPSSPLVP VSPRSDHNAP ESPSGDVADL YKDDDSPLAP RSPASPRKSP
     ENSPVGSPVK TTKVVISSDE DSDDEGPSSK KQRAVLSDSD ASDTEATTKK SRITLDSDDS
     DQEGDKQQKR KDLFGDDSDD DDFDRPKKQN DDLDELVKGD LEEDRGEQQR PIYDSDDDDG
     PSDRRGGRNF EWDFDKMLAE KKAERKRKTR RGKDGGIDII NDDDGMVAKL VEKMKHAAKS
     DRNANVERKP AFQKIKMLPE VKAIMLRAGI VEVLIENGFM SALSEWLAPL PDKCLPALDI
     RITVLKLLHN PRFWKLDRST LKQSGLGKAV MMLYKHPNET KENKAIANKL IGEWARPIYH
     LDTDYSTVSR QEREERDYSR MPEKRKKKLH SREEEPDEDE APKRPRIRDA EGLGPTKSLD
     LKPGDKGYIN RARVPKPSTK DYVIRPEWRV SGEFKGEKKA SGSKRYDQTL RDFQERTRKS
     KANRLVKVSL EGRNMGI