ID   IWS1_USTMA              Reviewed;         415 AA.
AC   Q4P7X6; A0A0D1C3C1;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-SEP-2015, sequence version 2.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Transcription factor IWS1;
GN   Name=IWS1; ORFNames=UMAG_10667;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA   Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA   Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA   Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA   Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA   Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA   Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA   Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA   Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA   Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA   Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA   Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT   maydis.";
RL   Nature 444:97-101(2006).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=521 / FGSC 9021;
RA   Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcription factor involved in RNA polymerase II
CC       transcription regulation. May function in both SPT15/TBP post-
CC       recruitment and recruitment steps of transcription (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00649}.
CC   -!- SIMILARITY: Belongs to the IWS1 family. {ECO:0000305}.
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DR   EMBL; CM003149; KIS68207.1; -; Genomic_DNA.
DR   RefSeq; XP_011390340.1; XM_011392038.1.
DR   AlphaFoldDB; Q4P7X6; -.
DR   SMR; Q4P7X6; -.
DR   STRING; 5270.UM03787P0; -.
DR   EnsemblFungi; KIS68207; KIS68207; UMAG_10667.
DR   GeneID; 23566666; -.
DR   KEGG; uma:UMAG_10667; -.
DR   VEuPathDB; FungiDB:UMAG_10667; -.
DR   eggNOG; KOG1793; Eukaryota.
DR   HOGENOM; CLU_045275_2_1_1; -.
DR   InParanoid; Q4P7X6; -.
DR   OrthoDB; 1103203at2759; -.
DR   Proteomes; UP000000561; Chromosome 10.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IBA:GO_Central.
DR   Gene3D; 1.20.930.10; -; 1.
DR   InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR   InterPro; IPR017923; TFIIS_N.
DR   Pfam; PF08711; Med26; 1.
DR   PROSITE; PS51319; TFIIS_N; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..415
FT                   /note="Transcription factor IWS1"
FT                   /id="PRO_0000083364"
FT   DOMAIN          251..328
FT                   /note="TFIIS N-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00649"
FT   REGION          1..154
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          381..415
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        78..92
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        93..118
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        128..143
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   415 AA;  46065 MW;  F4A8A40D6452E3B9 CRC64;
     MADQETAQSP IEEPSESAAQ AAAETLADAE IPATDAAADA SEGVVDDIDV IPPSDPEHLT
     TVVRGQDTAA AVRTAAIFDE DDEDEDDDGD EVGNDLPSFR KRDARDASNA DDPDAAVMRK
     KKKKRHHSPE EASSMRHVTD GEVEQEEEDP YANMTEAEIR RARTDRMIDE ALRAGKKKAP
     RKRAGEDDLD LLADEEVAAL RREMVTAADD DEEANRLKKP ATNKLKLLPK VVATLQKNHL
     QQSILDNNLL EGVKRWLEPL PDKSLPALNI QHQFFQILER MTIDTISLKM SGLGKVVVFY
     SMCSRVEPKI KRSAEHLIEV WSRPVLKRSS SYRDRHIASA EWNREALSQR AGPLVVGSVA
     DNNRRNVGIP QAVTAGFRVA PQSVAGQRSD SGHEARMANH KRLNQFKSRL KEAKR