ID   J1_VACCW                Reviewed;         153 AA.
AC   P07616; Q76ZT3;
DT   01-APR-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1988, sequence version 1.
DT   23-FEB-2022, entry version 66.
DE   RecName: Full=Protein J1;
DE   AltName: Full=Protein F7;
GN   OrderedLocusNames=VACWR093; ORFNames=J1R;
OS   Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain
OS   WR)).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10254;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2987815; DOI=10.1093/nar/13.3.985;
RA   Plucienniczak A., Schroeder E., Zettlmeissl G., Streeck R.E.;
RT   "Nucleotide sequence of a cluster of early and late genes in a conserved
RT   segment of the vaccinia virus genome.";
RL   Nucleic Acids Res. 13:985-998(1985).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Esposito J.J., Frace A.M., Sammons S.A., Olsen-Rasmussen M., Osborne J.,
RA   Wohlhueter R.;
RT   "Sequencing of the coding region of Vaccinia-WR to an average 9-fold
RT   redundancy and an error rate of 0.16/10kb.";
RL   Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   FUNCTION, INTERACTION WITH A45, SUBCELLULAR LOCATION, AND INDUCTION.
RX   PubMed=12208937; DOI=10.1128/jvi.76.19.9575-9587.2002;
RA   Chiu W.L., Chang W.;
RT   "Vaccinia virus J1R protein: a viral membrane protein that is essential for
RT   virion morphogenesis.";
RL   J. Virol. 76:9575-9587(2002).
RN   [4]
RP   IDENTIFICATION IN COMPLEX WITH A30; F10; A15; D2; D3 AND J1, AND FUNCTION.
RX   PubMed=15567438; DOI=10.1016/j.virol.2004.10.008;
RA   Szajner P., Jaffe H., Weisberg A.S., Moss B.;
RT   "A complex of seven vaccinia virus proteins conserved in all
RT   chordopoxviruses is required for the association of membranes and viroplasm
RT   to form immature virions.";
RL   Virology 330:447-459(2004).
RN   [5]
RP   FUNCTION, SUBUNIT, AND MUTAGENESIS OF PRO-132.
RX   PubMed=15956550; DOI=10.1128/jvi.79.13.8046-8056.2005;
RA   Chiu W.L., Szajner P., Moss B., Chang W.;
RT   "Effects of a temperature sensitivity mutation in the J1R protein component
RT   of a complex required for vaccinia virus assembly.";
RL   J. Virol. 79:8046-8056(2005).
CC   -!- FUNCTION: Late protein which is a part of a large complex required for
CC       early virion morphogenesis. This complex participates in the formation
CC       of virosomes and the incorporation of virosomal contents into nascent
CC       immature virions. J1 protein is required for DNA packaging during
CC       immature virions (IV) formation (Probable).
CC       {ECO:0000305|PubMed:12208937, ECO:0000305|PubMed:15567438,
CC       ECO:0000305|PubMed:15956550}.
CC   -!- SUBUNIT: Homodimer. Part of a complex composed of A30, G7, F10 kinase,
CC       A15, D2, D3, and J1. Interacts with A45. {ECO:0000269|PubMed:12208937,
CC       ECO:0000269|PubMed:15567438, ECO:0000269|PubMed:15956550}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:12208937}. Host
CC       cytoplasm {ECO:0000269|PubMed:12208937}. Note=Localizes in cytoplasmic
CC       virus factories. Probably located in between the core and the virion
CC       membrane.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       {ECO:0000269|PubMed:12208937}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae J1 family. {ECO:0000305}.
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DR   EMBL; X01978; CAA26015.1; -; Genomic_DNA.
DR   EMBL; AY243312; AAO89372.1; -; Genomic_DNA.
DR   PIR; F23092; QQVZF7.
DR   RefSeq; YP_232975.1; NC_006998.1.
DR   DIP; DIP-2174N; -.
DR   IntAct; P07616; 1.
DR   MINT; P07616; -.
DR   DNASU; 3707549; -.
DR   GeneID; 3707549; -.
DR   KEGG; vg:3707549; -.
DR   Proteomes; UP000000344; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR005006; Poxvirus_J1.
DR   Pfam; PF03338; Pox_J1; 1.
PE   1: Evidence at protein level;
KW   Host cytoplasm; Late protein; Reference proteome; Virion.
FT   CHAIN           1..153
FT                   /note="Protein J1"
FT                   /id="PRO_0000099588"
FT   MUTAGEN         132
FT                   /note="P->D,S: Blockage of virion morphogenesis at non-
FT                   permissve temperature and loss of association with A30L,
FT                   G7L, and F10L proteins."
FT                   /evidence="ECO:0000269|PubMed:15956550"
SQ   SEQUENCE   153 AA;  17922 MW;  6D34513D836B7FA0 CRC64;
     MDHNQYLLTM FFADDDSFFK YLASQDDESS LSDILQITQY LDFLLLLLIQ SKNKLEAVGH
     CYESLSEEYR QLTKFTDFQD FKKLFNKVPI VTDGRVKLNK GYLFDFVISL MRFKKESSLA
     TTAIDPVRYI DPRRNIAFSN VMDILKSNKV NNN