ID   J1_VAR67                Reviewed;         159 AA.
AC   P33004;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   23-FEB-2022, entry version 61.
DE   RecName: Full=Protein J1;
GN   ORFNames=J1R;
OS   Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=587200;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8383392; DOI=10.1016/0168-1702(93)90110-9;
RA   Shchelkunov S.N., Blinov V.M., Totmenin A.V., Marennikova S.S.,
RA   Kolykhalov A.A., Frolov I.V., Chizhikov V.E., Gytorov V.V., Gashikov P.V.,
RA   Belanov E.F., Belavin P.A., Resenchuk S.M., Andzhaparidze O.G.,
RA   Sandakhchiev L.S.;
RT   "Nucleotide sequence analysis of variola virus HindIII M, L, I genome
RT   fragments.";
RL   Virus Res. 27:25-35(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=8384129; DOI=10.1016/0014-5793(93)80041-r;
RA   Shchelkunov S.N., Blinov V.M., Sandakhchiev L.S.;
RT   "Genes of variola and vaccinia viruses necessary to overcome the host
RT   protective mechanisms.";
RL   FEBS Lett. 319:80-83(1993).
CC   -!- FUNCTION: Late protein which is a part of a large complex required for
CC       early virion morphogenesis. This complex participates in the formation
CC       of virosomes and the incorporation of virosomal contents into nascent
CC       immature virions. J1 protein is required for DNA packaging during
CC       immature virions (IV) formation (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. Part of a complex composed of A30, G7, F10 kinase,
CC       A15, D2, D3, and J1. Interacts with A45 (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion. Host cytoplasm {ECO:0000250}.
CC       Note=Localizes in cytoplasmic virus factories. Probably located in
CC       between the core and the virion membrane (By similarity).
CC       {ECO:0000250}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae J1 family. {ECO:0000305}.
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DR   EMBL; X67119; CAA47577.1; -; Genomic_DNA.
DR   EMBL; S55844; AAB24674.1; -; Genomic_DNA.
DR   EMBL; X69198; CAA49019.1; -; Genomic_DNA.
DR   PIR; S33092; S33092.
DR   RefSeq; NP_042122.1; NC_001611.1.
DR   PRIDE; P33004; -.
DR   GeneID; 1486464; -.
DR   KEGG; vg:1486464; -.
DR   Proteomes; UP000002060; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR005006; Poxvirus_J1.
DR   Pfam; PF03338; Pox_J1; 1.
PE   2: Evidence at transcript level;
KW   Host cytoplasm; Late protein; Reference proteome; Virion.
FT   CHAIN           1..159
FT                   /note="Protein J1"
FT                   /id="PRO_0000099589"
SQ   SEQUENCE   159 AA;  18483 MW;  0DDD10C8FCCFEC84 CRC64;
     MDHNQYLLTM FFADDDSFFK YLASQDDESS LSDILQITQY LDFLLLLLIQ SKNKLEAVGH
     CYESLSEEYR QLTKFTDSQD FKKLFNKVPI VTDGRVKLNK GYLFDFVISL MRFKKESALA
     TTAIDPVRYI DPRRDIAFSN VMDILKSNKA KNNYSLLSS