ID   J2_SOLLC                Reviewed;         250 AA.
AC   K4DEK0;
DT   30-AUG-2017, integrated into UniProtKB/Swiss-Prot.
DT   28-NOV-2012, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=MADS-box protein J2 {ECO:0000305};
DE   AltName: Full=MADS-box protein EBI {ECO:0000312|EMBL:AHB86542.1};
DE   AltName: Full=Protein EXTREME BRANCHED INFLORESCENCE {ECO:0000312|EMBL:AHB86542.1};
DE   AltName: Full=Protein JOINTLESS-2 {ECO:0000303|PubMed:28528644};
GN   Name=J2 {ECO:0000303|PubMed:28528644};
GN   Synonyms=EBI {ECO:0000312|EMBL:AHB86542.1};
GN   OrderedLocusNames=Solyc12g038510;
OS   Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC   Solanum subgen. Lycopersicon.
OX   NCBI_TaxID=4081;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Ailsa Craig;
RA   Dong T.;
RT   "Cloning and expression analysis of a MADS-box gene in tomato.";
RL   Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Heinz 1706;
RX   PubMed=22660326; DOI=10.1038/nature11119;
RG   Tomato Genome Consortium;
RT   "The tomato genome sequence provides insights into fleshy fruit
RT   evolution.";
RL   Nature 485:635-641(2012).
RN   [3]
RP   FUNCTION, AND BIOTECHNOLOGY.
RX   PubMed=28528644; DOI=10.1016/j.cell.2017.04.032;
RA   Soyk S., Lemmon Z.H., Oved M., Fisher J., Liberatore K.L., Park S.J.,
RA   Goren A., Jiang K., Ramos A., van der Knaap E., Van Eck J., Zamir D.,
RA   Eshed Y., Lippman Z.B.;
RT   "Bypassing negative epistasis on yield in tomato imposed by a domestication
RT   gene.";
RL   Cell 0:0-0(2017).
CC   -!- FUNCTION: MADS-box transcription factor that acts redundantly with EJ2
CC       to control meristem maturation and inflorescence architecture.
CC       {ECO:0000269|PubMed:28528644}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
CC   -!- BIOTECHNOLOGY: Combining natural and engineered alleles of J2 and EJ2
CC       provide a wide range of inflorescence complexity that allows breeding
CC       of higher yielding hybrids. {ECO:0000269|PubMed:28528644}.
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DR   EMBL; KF718834; AHB86542.1; -; mRNA.
DR   RefSeq; NP_001275579.1; NM_001288650.1.
DR   AlphaFoldDB; K4DEK0; -.
DR   SMR; K4DEK0; -.
DR   STRING; 4081.Solyc12g038510.1.1; -.
DR   PaxDb; K4DEK0; -.
DR   PRIDE; K4DEK0; -.
DR   EnsemblPlants; Solyc12g038510.2.1; Solyc12g038510.2.1; Solyc12g038510.2.
DR   GeneID; 101263981; -.
DR   Gramene; Solyc12g038510.2.1; Solyc12g038510.2.1; Solyc12g038510.2.
DR   KEGG; sly:101263981; -.
DR   eggNOG; KOG0014; Eukaryota.
DR   HOGENOM; CLU_053053_0_2_1; -.
DR   InParanoid; K4DEK0; -.
DR   OMA; VSYEHHH; -.
DR   OrthoDB; 1247594at2759; -.
DR   PhylomeDB; K4DEK0; -.
DR   Proteomes; UP000004994; Chromosome 12.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   CDD; cd00265; MADS_MEF2_like; 1.
DR   Gene3D; 3.40.1810.10; -; 1.
DR   InterPro; IPR033896; MADS_MEF2-like.
DR   InterPro; IPR002487; TF_Kbox.
DR   InterPro; IPR002100; TF_MADSbox.
DR   InterPro; IPR036879; TF_MADSbox_sf.
DR   Pfam; PF01486; K-box; 1.
DR   Pfam; PF00319; SRF-TF; 1.
DR   PRINTS; PR00404; MADSDOMAIN.
DR   SMART; SM00432; MADS; 1.
DR   SUPFAM; SSF55455; SSF55455; 1.
DR   PROSITE; PS51297; K_BOX; 1.
DR   PROSITE; PS00350; MADS_BOX_1; 1.
DR   PROSITE; PS50066; MADS_BOX_2; 1.
PE   1: Evidence at protein level;
KW   DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..250
FT                   /note="MADS-box protein J2"
FT                   /id="PRO_0000441032"
FT   DOMAIN          1..61
FT                   /note="MADS-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT   DOMAIN          87..177
FT                   /note="K-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00629"
SQ   SEQUENCE   250 AA;  28442 MW;  C24AB126ECD2290C CRC64;
     MGRGRVELKR IENKINRQVT FAKRRNGLLK KAYELSILCD AEVALIIFSS RGKLYEFSSA
     SSMMTTLEKY QQCSYASLDP MLPVSDTQMN YNEYVRLKAR VELLQRSQRH ILGEDLGTLN
     SKELEQLEHQ LDASLKKVRS KKTQSMLDQL ADLQEKEQML EEANKQLKNK LEESAARIPL
     GLSWGNNGGQ TMEYNRLPPQ TTAQPFFQPL RLNSSSPQFG YNPNMGANDH EVNAATTAHN
     INGFIPGWML