ID   J5_FOWPN                Reviewed;         137 AA.
AC   Q85281;
DT   29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Protein J5 homolog;
DE   AltName: Full=FPV136;
GN   OrderedLocusNames=FPV136; ORFNames=F11;
OS   Fowlpox virus (strain NVSL) (FPV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Avipoxvirus.
OX   NCBI_TaxID=928301;
OH   NCBI_TaxID=7742; Vertebrata.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Salisbury;
RX   PubMed=2820129; DOI=10.1016/0042-6822(87)90061-4;
RA   Drillien R., Spehner D., Villeval D., Lecocq J.-P.;
RT   "Similar genetic organization between a region of fowlpox virus DNA and the
RT   vaccinia virus HindIII J fragment despite divergent location of the
RT   thymidine kinase gene.";
RL   Virology 160:203-209(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10729156; DOI=10.1128/jvi.74.8.3815-3831.2000;
RA   Afonso C.L., Tulman E.R., Lu Z., Zsak L., Kutish G.F., Rock D.L.;
RT   "The genome of fowlpox virus.";
RL   J. Virol. 74:3815-3831(2000).
CC   -!- FUNCTION: Envelope protein part of the entry-fusion complex responsible
CC       for the virus membrane fusion with host cell membrane during virus
CC       entry. Also plays a role in cell-cell fusion (syncytium formation).
CC   -!- SUBUNIT: Part of a stable entry-fusion complex (EFC) which is at least
CC       composed of proteins A16, A21, A28, G3, G9, H2, J5, and L5. Formation
CC       of the viral membrane is necessary for the assembly of the complex.
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000305}; Single-pass
CC       membrane protein {ECO:0000305}. Note=Component of the mature virion
CC       (MV) membrane. The mature virion is located in the cytoplasm of
CC       infected cells and is probably released by cell lysis (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the poxviridae A16/G9/J5 family. {ECO:0000305}.
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DR   EMBL; M17418; AAA66424.1; -; Genomic_DNA.
DR   EMBL; AF198100; AAF44480.1; -; Genomic_DNA.
DR   RefSeq; NP_039099.1; NC_002188.1.
DR   GeneID; 1486684; -.
DR   KEGG; vg:1486684; -.
DR   Proteomes; UP000008597; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   InterPro; IPR004251; Pox_virus_G9/A16.
DR   Pfam; PF03003; Pox_G9-A16; 1.
PE   3: Inferred from homology;
KW   Fusion of virus membrane with host cell membrane;
KW   Fusion of virus membrane with host membrane; Membrane; Reference proteome;
KW   Signal-anchor; Transmembrane; Transmembrane helix; Viral envelope protein;
KW   Viral penetration into host cytoplasm; Virion; Virus entry into host cell.
FT   CHAIN           1..137
FT                   /note="Protein J5 homolog"
FT                   /id="PRO_0000099597"
FT   TOPO_DOM        1..114
FT                   /note="Virion surface"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        115..135
FT                   /note="Helical; Signal-anchor"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   137 AA;  15605 MW;  F7AF163C7F67318A CRC64;
     MDNVINDEAI FKYCESNPKD RDCLCIHPEP TIEKIGEDLL LPYYCWYEPC KRKTAKIPTA
     LRDNMKRCNL IDCSVSLGEI NLLDGILKVN NDCLSSHAIY AGYSVKPLEQ EIHLPIIDPK
     YLILGLAILA LIVLINW