JA2L_SOLLC
ID JA2L_SOLLC Reviewed; 356 AA.
AC A0A3Q7HH64;
DT 03-JUL-2019, integrated into UniProtKB/Swiss-Prot.
DT 10-APR-2019, sequence version 1.
DT 25-MAY-2022, entry version 12.
DE RecName: Full=NAC domain-containing protein JA2L {ECO:0000305};
DE AltName: Full=Protein JASMONIC ACID 2-LIKE {ECO:0000303|PubMed:25005917};
DE Short=Protein JA2-LIKE {ECO:0000303|PubMed:25005917};
GN Name=JA2L {ECO:0000303|PubMed:25005917};
GN OrderedLocusNames=Solyc07g063410 {ECO:0000305};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706;
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [2]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=25005917; DOI=10.1105/tpc.114.128272;
RA Du M., Zhai Q., Deng L., Li S., Li H., Yan L., Huang Z., Wang B., Jiang H.,
RA Huang T., Li C.B., Wei J., Kang L., Li J., Li C.;
RT "Closely related NAC transcription factors of tomato differentially
RT regulate stomatal closure and reopening during pathogen attack.";
RL Plant Cell 26:3167-3184(2014).
RN [3]
RP FUNCTION, AND INDUCTION.
RX PubMed=28733419; DOI=10.1105/tpc.16.00953;
RA Du M., Zhao J., Tzeng D.T.W., Liu Y., Deng L., Yang T., Zhai Q., Wu F.,
RA Huang Z., Zhou M., Wang Q., Chen Q., Zhong S., Li C.B., Li C.;
RT "MYC2 orchestrates a hierarchical transcriptional cascade that regulates
RT jasmonate-mediated plant immunity in tomato.";
RL Plant Cell 29:1883-1906(2017).
RN [4]
RP INDUCTION BY JASMONATE.
RX PubMed=30610166; DOI=10.1105/tpc.18.00405;
RA Liu Y., Du M., Deng L., Shen J., Fang M., Chen Q., Lu Y., Wang Q., Li C.,
RA Zhai Q.;
RT "MYC2 regulates the termination of jasmonate signaling via an
RT autoregulatory negative feedback loop.";
RL Plant Cell 31:106-127(2019).
CC -!- FUNCTION: Transcription factor that acts downstream of MYC2 in the
CC jasmonate-mediated response to Botrytis cinerea infection
CC (PubMed:28733419). With MYC2 forms a transcription module that
CC regulates wounding-responsive genes (PubMed:28733419). Involved in
CC jasmonate- and coronatine-mediated stomatal reopening in response to
CC Pseudomonas syringae pv tomato DC3000 infection (PubMed:25005917).
CC Regulates the expression of threonine deaminase 2 (TD2) through
CC promoter binding (PubMed:28733419). {ECO:0000269|PubMed:25005917,
CC ECO:0000269|PubMed:28733419}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00353,
CC ECO:0000269|PubMed:25005917}.
CC -!- TISSUE SPECIFICITY: Expressed in guard cells of the epidermis.
CC {ECO:0000269|PubMed:25005917}.
CC -!- INDUCTION: Induced by jasmonate (JA) (PubMed:25005917, PubMed:28733419,
CC PubMed:30610166). Induced by wounding (PubMed:28733419,
CC PubMed:25005917). Induced by infection with the fungal pathogen
CC Botrytis cinerea (PubMed:28733419). Induced by coronatine
CC (PubMed:25005917). {ECO:0000269|PubMed:25005917,
CC ECO:0000269|PubMed:28733419, ECO:0000269|PubMed:30610166}.
CC -!- DOMAIN: The NAC domain includes a DNA binding domain and a dimerization
CC domain. {ECO:0000255|PROSITE-ProRule:PRU00353}.
CC -!- MISCELLANEOUS: Plants silencing JA2L exhibit enhanced susceptibility to
CC the fungal pathogen Botrytis cinerea. {ECO:0000269|PubMed:28733419}.
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DR EMBL; CM001070; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001306107.1; NM_001319178.1.
DR AlphaFoldDB; A0A3Q7HH64; -.
DR SMR; A0A3Q7HH64; -.
DR STRING; 4081.Solyc07g063410.2.1; -.
DR EnsemblPlants; Solyc07g063410.3.1; Solyc07g063410.3.1; Solyc07g063410.3.
DR GeneID; 101248026; -.
DR Gramene; Solyc07g063410.3.1; Solyc07g063410.3.1; Solyc07g063410.3.
DR KEGG; sly:101248026; -.
DR OMA; EFFANST; -.
DR Proteomes; UP000004994; Chromosome 7.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 2.170.150.80; -; 1.
DR InterPro; IPR003441; NAC-dom.
DR InterPro; IPR036093; NAC_dom_sf.
DR Pfam; PF02365; NAM; 1.
DR SUPFAM; SSF101941; SSF101941; 1.
DR PROSITE; PS51005; NAC; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Plant defense; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..356
FT /note="NAC domain-containing protein JA2L"
FT /id="PRO_0000447552"
FT DOMAIN 14..162
FT /note="NAC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT DNA_BIND 111..168
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT REGION 163..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 356 AA; 40092 MW; EF45DA4D9952A6B3 CRC64;
MGVQEMDPLT QLSLPPGFRF YPTDEELLVQ YLCRKVAGHD FSLQIIAEID LYKFDPWVLP
SKAIFGEKEW YFFSPRDRKY PNGSRPNRVA GSGYWKATGT DKVITTDGRK VGIKKALVFY
IGKAPKGTKT NWIMHEYRLS EPTTKTGSSR LDDWVLCRIY KKNSGGQKSS CSDLQNKDIS
HASSSSSSSQ FDDMLESLPA IEDRYFSLPR VNSIRNFQQN DKINLQQLSS GNFDWAAMAG
LNSFPELRTG NQVPTPGNQT PVLINTNQYH NHNDNLNNFN EFFANSTALN FHGEVKFEGG
VDQEVESSVR AQRLNSVNPG FFQENSTGFS SSYTNSVPDP FGIRYPTQTV NMGFTG
