JA2_SOLLC
ID JA2_SOLLC Reviewed; 349 AA.
AC Q9SQL0;
DT 03-JUL-2019, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=NAC domain-containing protein JA2 {ECO:0000305};
DE AltName: Full=Protein JASMONIC ACID 2 {ECO:0000303|PubMed:25005917};
GN Name=JA2 {ECO:0000303|PubMed:25005917}; Synonyms=LEJA2 {ECO:0000303|Ref.1};
GN OrderedLocusNames=Solyc12g013620 {ECO:0000305};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Moneymaker;
RA Broday L., Lifschitz E.;
RT "Isolation of new regulatory genes specific to the jasmonic acid mediated
RT signalling pathway in plants.";
RL Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706;
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [3]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=25005917; DOI=10.1105/tpc.114.128272;
RA Du M., Zhai Q., Deng L., Li S., Li H., Yan L., Huang Z., Wang B., Jiang H.,
RA Huang T., Li C.B., Wei J., Kang L., Li J., Li C.;
RT "Closely related NAC transcription factors of tomato differentially
RT regulate stomatal closure and reopening during pathogen attack.";
RL Plant Cell 26:3167-3184(2014).
CC -!- FUNCTION: Transcription factor involved in abscisic acid-mediated
CC stomatal closure (PubMed:25005917). Regulates the expression of NCED1,
CC a gene involved in the biosynthesis of abscisic acid (ABA)
CC (PubMed:25005917). Required for the stomatal closure induced by the
CC bacterial pathogen Pseudomonas syringae pv tomato DC3000, but not for
CC stomatal reopening (PubMed:25005917). {ECO:0000269|PubMed:25005917}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00353,
CC ECO:0000269|PubMed:25005917}.
CC -!- TISSUE SPECIFICITY: Expressed in guard cells of the epidermis.
CC {ECO:0000269|PubMed:25005917}.
CC -!- INDUCTION: Induced by abscisic acid (ABA), dehydration and wounding.
CC {ECO:0000269|PubMed:25005917}.
CC -!- DOMAIN: The NAC domain includes a DNA binding domain and a dimerization
CC domain. {ECO:0000255|PROSITE-ProRule:PRU00353}.
CC -!- MISCELLANEOUS: Plants silencing JA2 exhibit a dwarf phenotype.
CC {ECO:0000269|PubMed:25005917}.
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DR EMBL; AF011555; AAF04915.1; -; mRNA.
DR EMBL; CM001075; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001233972.1; NM_001247043.1.
DR AlphaFoldDB; Q9SQL0; -.
DR SMR; Q9SQL0; -.
DR STRING; 4081.Solyc12g013620.1.1; -.
DR PaxDb; Q9SQL0; -.
DR PRIDE; Q9SQL0; -.
DR EnsemblPlants; Solyc12g013620.2.1; Solyc12g013620.2.1; Solyc12g013620.2.
DR GeneID; 543526; -.
DR Gramene; Solyc12g013620.2.1; Solyc12g013620.2.1; Solyc12g013620.2.
DR KEGG; sly:543526; -.
DR eggNOG; ENOG502QRBC; Eukaryota.
DR HOGENOM; CLU_035664_8_4_1; -.
DR InParanoid; Q9SQL0; -.
DR OMA; QTFEFRH; -.
DR OrthoDB; 925823at2759; -.
DR PhylomeDB; Q9SQL0; -.
DR Proteomes; UP000004994; Chromosome 12.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 2.170.150.80; -; 1.
DR InterPro; IPR003441; NAC-dom.
DR InterPro; IPR036093; NAC_dom_sf.
DR Pfam; PF02365; NAM; 1.
DR SUPFAM; SSF101941; SSF101941; 1.
DR PROSITE; PS51005; NAC; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..349
FT /note="NAC domain-containing protein JA2"
FT /id="PRO_0000447553"
FT DOMAIN 14..163
FT /note="NAC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT DNA_BIND 111..169
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT REGION 169..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..194
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 349 AA; 39475 MW; F568443EB83234D9 CRC64;
MGVQEKDPLL QLSLPPGFRF YPTDEELLVQ YLCKKVAGHD FPLQIIGEID LYKFDPWVLP
SKATFGEKEW YFFSPRDRKY PNGSRPNRVA GSGYWKATGT DKVITSQGRK VGIKKALVFY
VGKAPKGSKT NWIMHEYRLF ESSRKNNGSS KLDEWVLCRI YKKNSSGPKP LMSGLHSSNE
YSHGSSTSSS SQFDDMLESL PEMDDRFSNL PRLNSLKAEK FNLDRLDSAN FDWAILAGLK
PMPELGPANQ APGVQGQAQG HVNNHIHSDN NNMNFLNDVY AHPPNFRGNT KVESINLDEE
VESGKRNQRI DQSSYFQQSL NGFSQAYTNN VDQFGIQCPN QTLNLGFKQ
