JAGN_CAEEL
ID JAGN_CAEEL Reviewed; 189 AA.
AC Q9XUU9;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=Protein jagunal homolog {ECO:0000250|UniProtKB:Q7K1V5};
GN ORFNames=K05C4.2;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
RN [2]
RP IDENTIFICATION.
RX PubMed=17389229; DOI=10.1083/jcb.200701048;
RA Lee S., Cooley L.;
RT "Jagunal is required for reorganizing the endoplasmic reticulum during
RT Drosophila oogenesis.";
RL J. Cell Biol. 176:941-952(2007).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000250|UniProtKB:Q7K1V5}; Multi-pass membrane protein
CC {ECO:0000250|UniProtKB:Q7K1V5}.
CC -!- SIMILARITY: Belongs to the jagunal family. {ECO:0000305}.
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DR EMBL; Z81564; CAB04568.1; -; Genomic_DNA.
DR PIR; T23337; T23337.
DR RefSeq; NP_493559.1; NM_061158.5.
DR AlphaFoldDB; Q9XUU9; -.
DR SMR; Q9XUU9; -.
DR BioGRID; 38720; 2.
DR STRING; 6239.K05C4.2; -.
DR EPD; Q9XUU9; -.
DR PaxDb; Q9XUU9; -.
DR PeptideAtlas; Q9XUU9; -.
DR EnsemblMetazoa; K05C4.2.1; K05C4.2.1; WBGene00010579.
DR EnsemblMetazoa; K05C4.2.2; K05C4.2.2; WBGene00010579.
DR GeneID; 173335; -.
DR UCSC; K05C4.2.2; c. elegans.
DR CTD; 173335; -.
DR WormBase; K05C4.2; CE19970; WBGene00010579; -.
DR eggNOG; KOG4054; Eukaryota.
DR GeneTree; ENSGT00390000005596; -.
DR HOGENOM; CLU_121621_0_0_1; -.
DR InParanoid; Q9XUU9; -.
DR OMA; VWRGYPY; -.
DR OrthoDB; 1452436at2759; -.
DR PhylomeDB; Q9XUU9; -.
DR PRO; PR:Q9XUU9; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00010579; Expressed in larva and 4 other tissues.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0007029; P:endoplasmic reticulum organization; IBA:GO_Central.
DR GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR InterPro; IPR009787; Jagunal.
DR PANTHER; PTHR20955; PTHR20955; 1.
DR Pfam; PF07086; Jagunal; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..189
FT /note="Protein jagunal homolog"
FT /id="PRO_0000313618"
FT TOPO_DOM 1..34
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 56..78
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 79..99
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 100..105
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 106..126
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 127..150
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 172..189
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 189 AA; 22146 MW; C9CFCD3AC6FF9148 CRC64;
MSSRGVRAAG TDGTDFQNRQ RVAQHYQESA QYKSILKWFF VPHFLILVFM WLKVGSELLR
TNFGWKNAFF DRLDMPSAYP WEYVWCFSFI PIVLAIYSFQ RNKLKILHYA YYAEFVVGIF
PCMIGLGGQL PELMEYAQDM EGSNTPTFKG IFPMVIIWYI FFAVALQIHG FSMYFMHHLA
AAWAPVKRD
