ID   50510_ASFB7             Reviewed;         542 AA.
AC   Q89869;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   23-FEB-2022, entry version 60.
DE   RecName: Full=Protein MGF 505-10R;
GN   OrderedLocusNames=BA71R-031; ORFNames=A542R;
OS   African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS   (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10498;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA   Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA   Rodriguez J.F., Vinuela E.;
RT   "Analysis of the complete nucleotide sequence of African swine fever
RT   virus.";
RL   Virology 208:249-278(1995).
RN   [2]
RP   FUNCTION.
RX   PubMed=11238833; DOI=10.1128/jvi.75.7.3066-3076.2001;
RA   Zsak L., Lu Z., Burrage T.G., Neilan J.G., Kutish G.F., Moore D.M.,
RA   Rock D.L.;
RT   "African swine fever virus multigene family 360 and 530 genes are novel
RT   macrophage host range determinants.";
RL   J. Virol. 75:3066-3076(2001).
RN   [3]
RP   INDUCTION.
RX   PubMed=32075923; DOI=10.1128/jvi.00119-20;
RA   Cackett G., Matelska D., Sykora M., Portugal R., Malecki M., Baehler J.,
RA   Dixon L., Werner F.;
RT   "The African Swine Fever Virus Transcriptome.";
RL   J. Virol. 94:0-0(2020).
CC   -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC       efficient virus replication in macrophages.
CC       {ECO:0000269|PubMed:11238833}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       {ECO:0000269|PubMed:32075923}.
CC   -!- SIMILARITY: Belongs to the asfivirus MGF 505 family. {ECO:0000305}.
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DR   EMBL; U02468; AAA17791.1; -; Genomic_DNA.
DR   EMBL; U18466; AAA65262.1; -; Genomic_DNA.
DR   RefSeq; NP_042726.1; NC_001659.2.
DR   SMR; Q89869; -.
DR   GeneID; 22220414; -.
DR   KEGG; vg:22220414; -.
DR   Proteomes; UP000000624; Genome.
DR   InterPro; IPR004858; MGF_505.
DR   Pfam; PF03158; DUF249; 1.
PE   2: Evidence at transcript level;
KW   Early protein; Reference proteome.
FT   CHAIN           1..542
FT                   /note="Protein MGF 505-10R"
FT                   /id="PRO_0000373349"
SQ   SEQUENCE   542 AA;  63087 MW;  86F43F9E312D77F4 CRC64;
     MFSLQELCRK NIYILPYPLG KHVLQQLGLY WKGHGSLQRI GDDHVLLQQD LIFSINEALR
     MAAEEGNNEV VKLLLLWEGN LHYAIIGALE GDRYDLIHKY YEQIGDCHKI LPLIQDPQIF
     EKCHELSNSC NIRCLLEHAV KHNMLSILQK HKDQIRLHMA LTQILFELAC HERKNDIIRW
     IGYSLHIYHL ETIFDVAFAH KNLSLYVLGY ELLMHKVNTE AANIDLPNLL SYHLRTAAAG
     GLLNFMLETI KHGGCVDKTV LSAAIRYKHR KIVAHFIHQV PRKTVKKLLL YAVQARAPKK
     TLNLLLSSLN YAVHTITKQL VHNVINYSST LVVKLLLMRR KRKLNLVDAV LARLVKYSTY
     TDIVQFMGEF SVSPERVIKM AARESRTFLI EMISKAAWGN HPQTLIHHLK HLTNTMKPQS
     GKDLIIYTIH YIYLNSNMLV AEEEKNIFKL AKFYANHNAV NRFKQICEDY YILDARFKTL
     ILECFEIAVQ KNYPRIANIV DDYIRFLFYR GNITEEEIRE AYSLKDAEVY VDLKWLQQGE
     MV