JAL22_ARATH
ID JAL22_ARATH Reviewed; 458 AA.
AC O80950; A8MR44;
DT 11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Jacalin-related lectin 22;
DE AltName: Full=Myrosinase-binding protein-like At2g39310;
GN Name=JAL22; OrderedLocusNames=At2g39310; ORFNames=T16B24.5;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP FUNCTION, IDENTIFICATION IN THE PYK10 COMPLEX, GENE FAMILY, NOMENCLATURE,
RP AND DISRUPTION PHENOTYPE.
RX PubMed=18467340; DOI=10.1093/pcp/pcn075;
RA Nagano A.J., Fukao Y., Fujiwara M., Nishimura M., Hara-Nishimura I.;
RT "Antagonistic jacalin-related lectins regulate the size of ER body-type
RT beta-glucosidase complexes in Arabidopsis thaliana.";
RL Plant Cell Physiol. 49:969-980(2008).
CC -!- FUNCTION: Inhibitor-type lectin that may regulate the correct
CC polymerization and activation of BGLU23/PYK10 upon tissue damage.
CC {ECO:0000269|PubMed:18467340}.
CC -!- SUBUNIT: Component of the PYK10 complex, at least composed of
CC PYK10/BGLU23, BGLU21, BGLU22, JAL22, JAL23, PBP1/JAL30, PBP2/JAL31,
CC JAL32, JAL33, JAL34, JAL35, GLL22 and GLL23.
CC {ECO:0000269|PubMed:18467340}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=O80950-1; Sequence=Displayed;
CC Name=2;
CC IsoId=O80950-2; Sequence=VSP_056719;
CC -!- DISRUPTION PHENOTYPE: Larger PYK10 complexes.
CC {ECO:0000269|PubMed:18467340}.
CC -!- SIMILARITY: Belongs to the jacalin lectin family. {ECO:0000255|PROSITE-
CC ProRule:PRU01088, ECO:0000305}.
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DR EMBL; AC004697; AAC28979.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09658.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09659.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09660.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM61403.1; -; Genomic_DNA.
DR EMBL; AY054159; AAL06820.1; -; mRNA.
DR EMBL; AY069884; AAL47438.1; -; mRNA.
DR EMBL; AY142009; AAM98273.1; -; mRNA.
DR PIR; T02571; T02571.
DR RefSeq; NP_001078021.1; NM_001084552.1. [O80950-2]
DR RefSeq; NP_001154564.1; NM_001161092.1. [O80950-1]
DR RefSeq; NP_001323620.1; NM_001336765.1. [O80950-1]
DR RefSeq; NP_181463.1; NM_129488.4. [O80950-1]
DR AlphaFoldDB; O80950; -.
DR SMR; O80950; -.
DR BioGRID; 3854; 2.
DR STRING; 3702.AT2G39310.1; -.
DR MetOSite; O80950; -.
DR PaxDb; O80950; -.
DR PRIDE; O80950; -.
DR ProteomicsDB; 232260; -. [O80950-1]
DR EnsemblPlants; AT2G39310.1; AT2G39310.1; AT2G39310. [O80950-1]
DR EnsemblPlants; AT2G39310.2; AT2G39310.2; AT2G39310. [O80950-2]
DR EnsemblPlants; AT2G39310.3; AT2G39310.3; AT2G39310. [O80950-1]
DR EnsemblPlants; AT2G39310.4; AT2G39310.4; AT2G39310. [O80950-1]
DR GeneID; 818516; -.
DR Gramene; AT2G39310.1; AT2G39310.1; AT2G39310. [O80950-1]
DR Gramene; AT2G39310.2; AT2G39310.2; AT2G39310. [O80950-2]
DR Gramene; AT2G39310.3; AT2G39310.3; AT2G39310. [O80950-1]
DR Gramene; AT2G39310.4; AT2G39310.4; AT2G39310. [O80950-1]
DR KEGG; ath:AT2G39310; -.
DR Araport; AT2G39310; -.
DR TAIR; locus:2056138; AT2G39310.
DR eggNOG; ENOG502SCUZ; Eukaryota.
DR InParanoid; O80950; -.
DR OMA; FGENGHK; -.
DR OrthoDB; 551020at2759; -.
DR PhylomeDB; O80950; -.
DR PRO; PR:O80950; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O80950; baseline and differential.
DR Genevisible; O80950; AT.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR CDD; cd09612; Jacalin; 3.
DR Gene3D; 2.100.10.30; -; 3.
DR InterPro; IPR001229; Jacalin-like_lectin_dom.
DR InterPro; IPR033734; Jacalin-like_lectin_dom_plant.
DR InterPro; IPR036404; Jacalin-like_lectin_dom_sf.
DR Pfam; PF01419; Jacalin; 3.
DR SMART; SM00915; Jacalin; 3.
DR SUPFAM; SSF51101; SSF51101; 3.
DR PROSITE; PS51752; JACALIN_LECTIN; 3.
PE 1: Evidence at protein level;
KW Alternative splicing; Lectin; Reference proteome; Repeat.
FT CHAIN 1..458
FT /note="Jacalin-related lectin 22"
FT /id="PRO_0000072793"
FT DOMAIN 5..153
FT /note="Jacalin-type lectin 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01088"
FT DOMAIN 160..301
FT /note="Jacalin-type lectin 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01088"
FT DOMAIN 311..453
FT /note="Jacalin-type lectin 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01088"
FT VAR_SEQ 105..134
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_056719"
SQ SEQUENCE 458 AA; 50463 MW; EB01A410563EAAF8 CRC64;
MAKMYRKLAL CGGEGGQEWD DDVYEGVRKV YVGQDLNRIT YIKFEYVQED GEVVTTEYGT
TNQHPKEFVI QYPDEHIIAV EGSYHQVALI ATEVITSLVF KTSKGRKSPL FGPNLLGITT
GTKFVFEDEG KKIVGFHGRA GDAVDALGVY FVLDTTPFPL YKLDAQGGTD GRVWDDGSYD
GIKTLRIDQD NSRITYLEVE YEKDGEAKTC NHGGKGDTPS EFVLGYPDEY IKSVEATYQK
PNIFSNTAIT SLKFLTSKGR TSFFGYNVGK KFVLEQKGHR LVGFHGKEDA AIDALGAYFG
PVPTPTPLIP SKKLPAIGGN EGVTWDDGVY DGVRKILVGQ GNDGVSFVKF EYSKGKDLVP
GDDHGKKTLL GAEEFVLEDG EYLMNIDGYY DKIFGVEEPI IVCLQFKTNK RESMPFGMDS
GKKFSLGEEG HKIVGFHGQA SDVVHSIGVT IVPITTTE
