JASON_ARATH
ID JASON_ARATH Reviewed; 481 AA.
AC F4IDQ5; Q8RX34; Q9SHK5;
DT 29-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 25-MAY-2022, entry version 58.
DE RecName: Full=Protein JASON {ECO:0000305};
GN Name=JASON {ECO:0000303|PubMed:21257792};
GN OrderedLocusNames=At1g06660 {ECO:0000312|Araport:AT1G06660};
GN ORFNames=F12K11.5 {ECO:0000312|EMBL:AAF24810.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 145-481.
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=21257792; DOI=10.1104/pp.110.170415;
RA De Storme N., Geelen D.;
RT "The Arabidopsis mutant jason produces unreduced first division restitution
RT male gametes through a parallel/fused spindle mechanism in meiosis II.";
RL Plant Physiol. 155:1403-1415(2011).
CC -!- FUNCTION: Required for normal spindle orientation at male meiosis II
CC and normal formation of tetrad of microspores. Acts as positive
CC regulator of PS1 in male sporogenesis. Not involved in female meiosis.
CC {ECO:0000269|PubMed:21257792}.
CC -!- DISRUPTION PHENOTYPE: Diploid pollen grains (dyads of spores instead of
CC tetrads) due to defective meiosis II. Abnormal spindle orientation at
CC meiosis II. {ECO:0000269|PubMed:21257792}.
CC -!- MISCELLANEOUS: Diploid male spores in jason mutants give rise to viable
CC diploid pollen grains and spontaneous triploid plants in the next
CC generation. {ECO:0000269|PubMed:21257792}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF24810.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BX814233; Type=Miscellaneous discrepancy; Note=Sequencing erros.; Evidence={ECO:0000305};
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DR EMBL; AC007592; AAF24810.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE28020.1; -; Genomic_DNA.
DR EMBL; BX814233; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; AY090923; AAM13918.1; -; mRNA.
DR RefSeq; NP_172151.2; NM_100543.5.
DR AlphaFoldDB; F4IDQ5; -.
DR STRING; 3702.AT1G06660.1; -.
DR iPTMnet; F4IDQ5; -.
DR PaxDb; F4IDQ5; -.
DR PRIDE; F4IDQ5; -.
DR ProteomicsDB; 238984; -.
DR EnsemblPlants; AT1G06660.1; AT1G06660.1; AT1G06660.
DR GeneID; 837176; -.
DR Gramene; AT1G06660.1; AT1G06660.1; AT1G06660.
DR KEGG; ath:AT1G06660; -.
DR Araport; AT1G06660; -.
DR TAIR; locus:2009165; AT1G06660.
DR eggNOG; ENOG502QUII; Eukaryota.
DR HOGENOM; CLU_034423_1_0_1; -.
DR InParanoid; F4IDQ5; -.
DR OMA; SCGTISQ; -.
DR OrthoDB; 1022250at2759; -.
DR PRO; PR:F4IDQ5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4IDQ5; baseline and differential.
DR GO; GO:0007142; P:male meiosis II; IMP:TAIR.
DR GO; GO:0009556; P:microsporogenesis; IMP:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEP:TAIR.
DR InterPro; IPR039300; JASON.
DR PANTHER; PTHR33318; PTHR33318; 1.
PE 2: Evidence at transcript level;
KW Meiosis; Reference proteome.
FT CHAIN 1..481
FT /note="Protein JASON"
FT /id="PRO_0000433006"
FT REGION 226..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..244
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 481 AA; 53142 MW; 060F14C954981E5E CRC64;
MRRLLMNRNL SPLCRSVLRF IDLSVCRAMA CFLDCFRARD NRSTSNLVSH SSLANSRKAQ
DSQNDLSALF LSEEKSASSP CLDKERFDLD SIHIDKGLRD EARFLKACGT IPETPIEIRK
ASQKLSPQHS GSSHFHSWIS SSSSMGSRLA ESSTPMKACE EVGRPSFTSE QTASSCVIDV
RDNARISSAS SDGTEVESVG TAIKGELDRT ARPTFTAGKN KSVRFECDLD QSNSSNSSEN
GSSRKPEMGG KICFTVSSPN PTPLKLSDEM QTPGTIYPAN MESGGRGRPR IRSQFVHSVS
NIMENASLYK VYKDSHEGLD YEEQIEAETP SSETYGEKVE ESSDEKLSKF EASFSPWLNQ
INENIAALNE RTPGVGVITP GDRPIIGLVA AQWIENEQTE ISPKMWDGNG IPNSTTKYKE
DQKVSWHATP FEVRLEKALS EEGGQSLFPQ RKLEVMMEEV EGDTDISQLH HSVQPNSVVS
F
