ID   JETC_BACCQ              Reviewed;        1104 AA.
AC   B9IS85;
DT   03-AUG-2022, integrated into UniProtKB/Swiss-Prot.
DT   03-AUG-2022, sequence version 2.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Wadjet protein JetC {ECO:0000303|PubMed:29371424};
DE   AltName: Full=Probable ATPase JetC {ECO:0000305|PubMed:29371424};
GN   Name=jetC {ECO:0000303|PubMed:29371424};
GN   OrderedLocusNames=BCQ_1017 {ECO:0000312|EMBL:ACM11447.1};
OS   Bacillus cereus (strain Q1).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=361100;
RN   [1] {ECO:0000312|EMBL:ACM11447.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Q1;
RX   PubMed=19060151; DOI=10.1128/jb.01629-08;
RA   Xiong Z., Jiang Y., Qi D., Lu H., Yang F., Yang J., Chen L., Sun L., Xu X.,
RA   Xue Y., Zhu Y., Jin Q.;
RT   "Complete genome sequence of the extremophilic Bacillus cereus strain Q1
RT   with industrial applications.";
RL   J. Bacteriol. 191:1120-1121(2009).
RN   [2]
RP   FUNCTION, DISRUPTION PHENOTYPE, AND MUTAGENESIS OF GLU-1025.
RC   STRAIN=Q1;
RX   PubMed=29371424; DOI=10.1126/science.aar4120;
RA   Doron S., Melamed S., Ofir G., Leavitt A., Lopatina A., Keren M.,
RA   Amitai G., Sorek R.;
RT   "Systematic discovery of antiphage defense systems in the microbial
RT   pangenome.";
RL   Science 359:0-0(2018).
CC   -!- FUNCTION: Component of antiplasmid transformation system Wadjet type I,
CC       composed of JetA, JetB, JetC and JetD. Expression of Wadjet type I in
CC       B.subtilis (strain BEST7003) reduces the transformation efficiency of
CC       plasmid pHCMC05 (PubMed:29371424). May be an ATPase (Probable).
CC       {ECO:0000269|PubMed:29371424, ECO:0000305|PubMed:29371424}.
CC   -!- DISRUPTION PHENOTYPE: When this gene is missing the Wadjet system does
CC       not confer plasmid-transformation resistance in B.subtilis.
CC       {ECO:0000269|PubMed:29371424}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ACM11447.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; CP000227; ACM11447.1; ALT_INIT; Genomic_DNA.
DR   SMR; B9IS85; -.
DR   EnsemblBacteria; ACM11447; ACM11447; BCQ_1017.
DR   KEGG; bcq:BCQ_1017; -.
DR   HOGENOM; CLU_009040_1_0_9; -.
DR   OMA; ETQTPFY; -.
DR   Proteomes; UP000000441; Chromosome.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   1: Evidence at protein level;
FT   CHAIN           1..1104
FT                   /note="Wadjet protein JetC"
FT                   /id="PRO_0000456347"
FT   MUTAGEN         1025
FT                   /note="E->Q: No longer protects against plasmid
FT                   transformation."
FT                   /evidence="ECO:0000269|PubMed:29371424"
SQ   SEQUENCE   1104 AA;  130319 MW;  F305AD4725A84D08 CRC64;
     MKKLRLINWH YYSDETILFG KQTVISGHTG AGKSTVIDAL QVLFISDERK IKFNSAAYEE
     ANRTLINYLR GKIGTEEKPF VREGYFTTYI VAEFYDEKAG ESFVIGISID VFKDDEKVKE
     YFIIPKSEIN MISFFSTKDE KRYVEKQADF CKKIREQFPE AIIEKSSNQY QKALLQRFGG
     LHERFVKTFA RALSFKPIDN MKDFVYKNIL DEKELKIDVM RNIFQTHEEL QRELEELKER
     KEELERIDNI YLECVKLEAD ISIQEYVLRG LEYLLIQEEK SMCKKSIEQR EKELRKCESD
     QKKTAEQKEH ARKKETEYEI KIKDSAEQKR QKQLQEQIAQ AKKECGDLEC TKNIYVHSLA
     REEKDVSSLL NYQGNEYFSL SKDEKHALEI GRDCLAFLSH NDGTGGNREE QTLNKLGESL
     KRISGRFYKS TAELEHRSAE LKTEEKELLS DIENLKRRKR PYPMSVEKLK GLLEKHLEDQ
     SKVWILCEEL EIKNDKWRNA LEGYLNTQRF DILVEPHMFA TALSIYEKEK WNLGLEGVGL
     VDTEKEQTYL GKVEKGSLAE EIVGGNPIVQ ARIHHLLGRV IKADNEQELR KYKTAVTATC
     MSYQRLVARQ IPRKVYETPY IGAHAIQKQL EIKEENLKEI QTELQIVGYY IKDFKKWIEI
     LEDKQSDYKN YILNFSLNDS ILEFNKNINK WKSELNTLDL SRLESLRQKL KEWNGKYNQF
     NGEEGRLFEQ IGKVKEELQR VNAELWKKEK AATEILEKWK NWKFEYRIEL LQEAEQRYEQ
     AISTNKAYGA IKNKYENNKK ENQNKYEEKR GFLESERKSY NEARTFQGII QAKDNKQYEE
     ALRKIANLDI PKFEQEIKET LQQAEEEFQS HFIYKMREAI QAARREFNQL NHALGRFKFR
     NDTYRFVIKP SEQYKKFYDV IMDERVQPEI SLFDFGDEDR AEILKDLFGR LVVGEYGENE
     EFVDYRNYLD FDLSINNENG TRFMSNLLRE QSGGETQTPF YIAILASFQH LYRNKNTIRL
     VVFDEAFNKM DEERIQISLR LIKQLDLQLI AAVPDEKMAH MAAEADTAII INRIGHSCFT
     DILSYPREDE AIGLQEQDSF SLIE