JHEB_TRINI
ID JHEB_TRINI Reviewed; 63 AA.
AC P30810;
DT 01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1993, sequence version 1.
DT 02-JUN-2021, entry version 57.
DE RecName: Full=Juvenile hormone esterase, isoform B;
DE Short=JH esterase;
DE Short=JHE-B;
DE EC=3.1.1.59;
DE Flags: Fragments;
OS Trichoplusia ni (Cabbage looper).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC Noctuidae; Plusiinae; Trichoplusia.
OX NCBI_TaxID=7111;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=7679289; DOI=10.1016/0167-4838(93)90219-h;
RA Jones G., Manczak M., Wozniak M., Ko'Rrati R.;
RT "Characterization of two major isoforms of juvenile hormone esterase from
RT Trichoplusia ni (Lepidoptera).";
RL Biochim. Biophys. Acta 1161:235-243(1993).
CC -!- FUNCTION: JH esterase plays a crucial role in the decrease of JH
CC activity in lepidopteran insects, by hydrolyzing the methyl ester of
CC JH. It is also involved in the transport of JH.
CC {ECO:0000250|UniProtKB:P19985}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + juvenile hormone I = H(+) + juvenile hormone I
CC carboxylate + methanol; Xref=Rhea:RHEA:46916, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:17790, ChEBI:CHEBI:83641,
CC ChEBI:CHEBI:87109; EC=3.1.1.59;
CC Evidence={ECO:0000250|UniProtKB:P19985};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + juvenile hormone III = H(+) + juvenile hormone III
CC carboxylate + methanol; Xref=Rhea:RHEA:46912, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:17790, ChEBI:CHEBI:27493,
CC ChEBI:CHEBI:83274; EC=3.1.1.59;
CC Evidence={ECO:0000250|UniProtKB:P19985};
CC -!- TISSUE SPECIFICITY: Fat body, the site of their biosynthesis, and the
CC hemolymph where it is secreted.
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000305}.
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DR PIR; S29654; S29654.
DR BindingDB; P30810; -.
DR ChEMBL; CHEMBL2366569; -.
DR Proteomes; UP000322000; Genome assembly.
DR GO; GO:0004453; F:juvenile-hormone esterase activity; IEA:UniProtKB-EC.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Glycoprotein; Hydrolase; Reference proteome;
KW Serine esterase.
FT CHAIN 1..>63
FT /note="Juvenile hormone esterase, isoform B"
FT /id="PRO_0000070293"
FT CARBOHYD 20
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000305"
FT UNSURE 20
FT UNSURE 24
FT UNSURE 31
FT UNSURE 35
FT NON_CONS 12..13
FT /evidence="ECO:0000305"
FT NON_CONS 23..24
FT /evidence="ECO:0000305"
FT NON_CONS 34..35
FT /evidence="ECO:0000305"
FT NON_CONS 47..48
FT /evidence="ECO:0000305"
FT NON_TER 63
SQ SEQUENCE 63 AA; 6947 MW; 3B647674F14BBABA CRC64;
LPSLSADAEA PSKIDTAYYN GTKTXXAPVY QYQFGVGXIE XLTYVFKGSQ YQDIESPTAY
QSK