ID   JHY_BOVIN               Reviewed;         773 AA.
AC   Q2T9M9;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Jhy protein homolog;
GN   Name=JHY;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the normal development of cilia in brain
CC       ependymal cells lining the ventricular surfaces.
CC       {ECO:0000250|UniProtKB:E9Q793}.
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DR   EMBL; BC111348; AAI11349.1; -; mRNA.
DR   RefSeq; NP_001033297.1; NM_001038208.1.
DR   AlphaFoldDB; Q2T9M9; -.
DR   SMR; Q2T9M9; -.
DR   STRING; 9913.ENSBTAP00000047568; -.
DR   PRIDE; Q2T9M9; -.
DR   GeneID; 615337; -.
DR   KEGG; bta:615337; -.
DR   CTD; 79864; -.
DR   OrthoDB; 1114555at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0035082; P:axoneme assembly; IBA:GO_Central.
DR   GO; GO:0007420; P:brain development; IBA:GO_Central.
DR   InterPro; IPR027968; JHY.
DR   PANTHER; PTHR14726; PTHR14726; 1.
DR   Pfam; PF15261; JHY; 1.
PE   2: Evidence at transcript level;
KW   Cilium biogenesis/degradation; Reference proteome.
FT   CHAIN           1..773
FT                   /note="Jhy protein homolog"
FT                   /id="PRO_0000281675"
FT   REGION          1..247
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          325..373
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          496..526
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          596..615
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          713..743
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..26
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        27..48
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        63..81
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        82..100
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        114..137
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        144..158
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        173..204
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        218..232
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        332..352
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        353..368
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        500..517
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        725..740
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   773 AA;  87993 MW;  746FFFC10693F8D1 CRC64;
     MSHSKFIPTV SIQSPVHHTN IKVQSTEPSF KKEDLHLISK DSLESDSESP TQKIKSQSDL
     EDQIQDNDME PDSLEEENLS ETEEEASRKA AQRAKKENLH TQDAAAINSR QPTEDKYSHI
     RYDPNWKSKK EEGKLLPVEA LPESVDSSTE NLTLNPLYPS KEPSMDLSAG KGEQKSPRST
     ASLLGSEFVS PNYELSTHRT EPFSVLSDSD PEEKSSNLSR YLKSSSSRSE AFLPGSRGPR
     RRKSKQYFVE KNKLTLGLPT PRMDSYLQLH NKKRGEGHLE QISYPVRVTD KTSIQNARET
     GNVAIDPEDK WHQRAQQLKD YQEHWSQYEH EKSSSGPRGQ SSETTNGQQP SRKPAKHKIR
     KQRRHRHGPK SLVTEELVVS QGNQNNTPRH QQNPNKPIDT EVTQETVVIM NATNDDLQYS
     SVLRSQDPTV TSNQYAPLHQ ISDKVLYKNP ARYYPVTNAN RERGHNDQEE KRFSYQQLHI
     DTLSDMHLNY LHELNKKHPS GSQKGSQSVS NINRQASTEK KKQPKLAYTE TKYKNLEILW
     KFHSSSEEQP AKASPDSRLS QIMEQHQQAL LQLTEVQPHE GASPGLTLPP ILPRVESESQ
     LSSERSQRNQ VKISRSNSES YLFQLEKGKK HRKRSSIKSS KLKGYQNRDV KLGGLGPDLE
     SIRDKMQKLI QQKEYAKQVK EYNMKALSIP SKPQTAITEN KSAVPRQKAL EYAKTIPKPK
     PSNLSDQASK EKKTPTHAGK EDTLPEISLL EVLQNRHERE KQAVAAFKVL HIV