ID   50510_ASFM2             Reviewed;         543 AA.
AC   Q65114;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 50.
DE   RecName: Full=Protein MGF 505-10R;
GN   OrderedLocusNames=Mal-041;
OS   African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10500;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8030263; DOI=10.1006/viro.1994.1426;
RA   Yozawa T., Kutish G.F., Afonso C.L., Lu Z., Rock D.L.;
RT   "Two novel multigene families, 530 and 300, in the terminal variable
RT   regions of African swine fever virus genome.";
RL   Virology 202:997-1002(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC       efficient virus replication in macrophages.
CC       {ECO:0000250|UniProtKB:Q89869}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the asfivirus MGF 505 family. {ECO:0000305}.
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DR   EMBL; AY261361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; U03761; AAA50527.1; -; Genomic_DNA.
DR   SMR; Q65114; -.
DR   Proteomes; UP000000860; Genome.
DR   InterPro; IPR004858; MGF_505.
DR   Pfam; PF03158; DUF249; 1.
PE   3: Inferred from homology;
KW   Early protein.
FT   CHAIN           1..543
FT                   /note="Protein MGF 505-10R"
FT                   /id="PRO_0000373351"
SQ   SEQUENCE   543 AA;  63279 MW;  1ECE56C5D8B609B5 CRC64;
     MFSLQELCRK NIYILPYPLG EHVLQQLGLY WKGYGSLQRI GDDHVLLQQD LIFSINEALR
     MAGEEGNNEV VKLLLLWEGN LHYAIIGALE GDRYDLIHKY YGQIGDCHKI LPLIQDPQIF
     EKCHELSTSC NIRCLLEHAV KHNMLSILQK HKDQIRFHLA LTQILFELAC HERKNDIIRW
     IGYSLHIYQL ETIFDVAFAH KNLSLYVLGY ELLMHKVNTE AANIDLPNLL SYHLRTAAAG
     GLLHFMFETL KHGGYVDKAV LSAAISYKHR KVVAHFIHQV PRKTVEKLLL HAVQTRAPKK
     TLNLLLSSLN YSVHPITKQL VRNVVDYRST LIVKLLLMRR KRKLNLVDAV LARLVRYSTY
     TDTVKFMGEF SVSPEKVIKM AARESRTFMI EMISKAVWKN HPQTMIHHLK QLADTMKPQS
     GKDLIIYTIH YIYQSSNLLV AEEEKNIFKL AKFYANHNSV NRFKQICEDY YTLDVDTRFK
     TLILECFEIA VQKNYPRIAT IVDDFIRFLF YKGDITEEEI SEAYSLKNAE LYVDLKWLQQ
     EEN