JIP5_ASPFU
ID JIP5_ASPFU Reviewed; 416 AA.
AC Q4WNA1;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2005, sequence version 1.
DT 25-MAY-2022, entry version 95.
DE RecName: Full=WD repeat-containing protein jip5;
GN Name=jip5; ORFNames=AFUA_6G07080;
OS Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS A1100) (Aspergillus fumigatus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA Barrell B.G., Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
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DR EMBL; AAHF01000006; EAL88563.1; -; Genomic_DNA.
DR RefSeq; XP_750601.1; XM_745508.1.
DR AlphaFoldDB; Q4WNA1; -.
DR SMR; Q4WNA1; -.
DR STRING; 746128.CADAFUBP00007109; -.
DR EnsemblFungi; EAL88563; EAL88563; AFUA_6G07080.
DR GeneID; 3508814; -.
DR KEGG; afm:AFUA_6G07080; -.
DR VEuPathDB; FungiDB:Afu6g07080; -.
DR eggNOG; KOG2444; Eukaryota.
DR HOGENOM; CLU_052691_0_0_1; -.
DR InParanoid; Q4WNA1; -.
DR OMA; QTHHPHD; -.
DR OrthoDB; 1173229at2759; -.
DR Proteomes; UP000002530; Chromosome 6.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR SUPFAM; SSF50978; SSF50978; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Repeat; WD repeat.
FT CHAIN 1..416
FT /note="WD repeat-containing protein jip5"
FT /id="PRO_0000333547"
FT REPEAT 9..48
FT /note="WD 1"
FT REPEAT 73..112
FT /note="WD 2"
FT REPEAT 118..159
FT /note="WD 3"
FT REPEAT 222..263
FT /note="WD 4"
FT REPEAT 319..356
FT /note="WD 5"
FT REGION 39..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 353..416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 416 AA; 44160 MW; 3D2FAA5D29BE7D60 CRC64;
MFDTVCTLPL SADLFSQALH PKEPIVSVGL STGHVQTFRL PSEESDTDND GAESTSSSRN
GKGHIDTMWR TRRHKGSCRC LGFGVDGEML YSAGTDGLVK AAKAETGVVE NKIAIPPAKD
GSVDAPTIVH ALSPQTLLLA TDSSALHLYD LRIPFSPVSA RPQQTHHPHD DYISSLTPLP
PSDTSTSGFS KQWVTTGGTT LAVTDLRRGV LVRSEDQEEE LVSSVYIGGL RAGGTSRGEK
VIVGGSSGVL TLWEKGAWDD QDERIYVQRE AGGGESLETL AVVPDELGKG KMIAVGLGSG
GVKFVRMGVN KVVSEVMHDE TEGVIGLGFD VEGRMVSGGG QIVKVWHEAV DSDEMDGDTI
GGKRMFGSGS DSDDSDDGDD SDDSDRGSRK AAQPQRKKRK NKGKGGQDIM GFADID