ID   JIP5_CANAL              Reviewed;         542 AA.
AC   Q5AQ62; A0A1D8PEE9; Q5APM0;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2017, sequence version 2.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=WD repeat-containing protein JIP5;
GN   Name=JIP5; OrderedLocusNames=CAALFM_C108870CA;
GN   ORFNames=CaO19.12208, CaO19.4746;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP017623; AOW26524.1; -; Genomic_DNA.
DR   RefSeq; XP_723432.2; XM_718339.2.
DR   AlphaFoldDB; Q5AQ62; -.
DR   SMR; Q5AQ62; -.
DR   STRING; 237561.Q5AQ62; -.
DR   GeneID; 3634922; -.
DR   KEGG; cal:CAALFM_C108870CA; -.
DR   CGD; CAL0000174164; JIP5.
DR   VEuPathDB; FungiDB:C1_08870C_A; -.
DR   eggNOG; KOG2444; Eukaryota.
DR   HOGENOM; CLU_035623_0_0_1; -.
DR   InParanoid; Q5AQ62; -.
DR   OrthoDB; 676458at2759; -.
DR   PRO; PR:Q5AQ62; -.
DR   Proteomes; UP000000559; Chromosome 1.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:EnsemblFungi.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..542
FT                   /note="WD repeat-containing protein JIP5"
FT                   /id="PRO_0000333552"
FT   REPEAT          125..170
FT                   /note="WD 1"
FT   REPEAT          177..216
FT                   /note="WD 2"
FT   REPEAT          265..309
FT                   /note="WD 3"
FT   REPEAT          372..409
FT                   /note="WD 4"
FT   REGION          400..542
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        405..457
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        458..497
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        506..542
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   542 AA;  60688 MW;  18CA1B2C7B990EAF CRC64;
     MGKKKSNSSN AAQILESSVS PILEINYNDP LFTAASHPTK PILLSGLATG HVYCNSYDAE
     KLEELTQSKR EEYATLEKQA YTQGKIPHIN KSVSQSKKKW WTIVQDNTEI PNDGDLINTN
     WKTKRHKGSC RHAIFEPLEN SVGDFIYTCG TDNIIKKAST ETGKVVGKVD VSSDYSNKKD
     LLTKLCHSVT HPFLLSGTED GHVLVYDSAN LNSNKLKFKV ESAHDDSINH ILAMPAVSAY
     HYLTLGSTTL AHIDIRKGII TQSDDQEDEL LAMCFPSDEV SQSNDTVLVS HGEGLITIWK
     NSKNKLMDQL SRVKVNKSAS IDTIISTMNA DNEDMANSVW CGDSEGLLHR INYKRGRVVE
     TRLHSVAKGK HGAVDEVGIL DIDFDYRLVS AGMDTLKIWS NTQDEEQNDE DDDDDNDDSD
     GDDSESVSGE DSWSDISSSD EELDTNPDDD SDKDDVDVED DLQLRKKRDD ISQLISKPKR
     KTIDINKLTK ATKNTQPEDD EEDQEVPEPS QKKQKVKEKK LTTKQLRNMQ KHEHGIRKFE
     GL