ID   JIP5_COPC7              Reviewed;         408 AA.
AC   A8NZM5;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 2.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=WD repeat-containing protein JIP5;
GN   Name=JIP5; ORFNames=CC1G_06910;
OS   Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)
OS   (Inky cap fungus) (Hormographiella aspergillata).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Psathyrellaceae; Coprinopsis.
OX   NCBI_TaxID=240176;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003;
RX   PubMed=20547848; DOI=10.1073/pnas.1003391107;
RA   Stajich J.E., Wilke S.K., Ahren D., Au C.H., Birren B.W., Borodovsky M.,
RA   Burns C., Canbaeck B., Casselton L.A., Cheng C.K., Deng J., Dietrich F.S.,
RA   Fargo D.C., Farman M.L., Gathman A.C., Goldberg J., Guigo R., Hoegger P.J.,
RA   Hooker J.B., Huggins A., James T.Y., Kamada T., Kilaru S., Kodira C.,
RA   Kuees U., Kupfer D., Kwan H.S., Lomsadze A., Li W., Lilly W.W., Ma L.-J.,
RA   Mackey A.J., Manning G., Martin F., Muraguchi H., Natvig D.O.,
RA   Palmerini H., Ramesh M.A., Rehmeyer C.J., Roe B.A., Shenoy N., Stanke M.,
RA   Ter-Hovhannisyan V., Tunlid A., Velagapudi R., Vision T.J., Zeng Q.,
RA   Zolan M.E., Pukkila P.J.;
RT   "Insights into evolution of multicellular fungi from the assembled
RT   chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).";
RL   Proc. Natl. Acad. Sci. U.S.A. 107:11889-11894(2010).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAU84048.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AACS02000006; EAU84048.2; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_001837704.2; XM_001837652.2.
DR   AlphaFoldDB; A8NZM5; -.
DR   SMR; A8NZM5; -.
DR   STRING; 240176.A8NZM5; -.
DR   EnsemblFungi; EAU84048; EAU84048; CC1G_06910.
DR   GeneID; 6014265; -.
DR   KEGG; cci:CC1G_06910; -.
DR   HOGENOM; CLU_035848_2_1_1; -.
DR   InParanoid; A8NZM5; -.
DR   OrthoDB; 1173229at2759; -.
DR   Proteomes; UP000001861; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 2.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..408
FT                   /note="WD repeat-containing protein JIP5"
FT                   /id="PRO_0000333556"
FT   REPEAT          5..44
FT                   /note="WD 1"
FT   REPEAT          50..86
FT                   /note="WD 2"
FT   REPEAT          87..130
FT                   /note="WD 3"
FT   REPEAT          133..172
FT                   /note="WD 4"
FT   REPEAT          177..216
FT                   /note="WD 5"
FT   REPEAT          221..267
FT                   /note="WD 6"
FT   REGION          311..408
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        312..341
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        368..408
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   408 AA;  44451 MW;  F1485F300737046F CRC64;
     MPEIPVGSQI FDVVFHPSSA IAYTGLLNGH IKAFAYGEQG DSHNLFSLRP SKRSCRGLSL
     NGDGSKLYAV GKSKALHIVD TTTTDIDARS AAHDCAINRV KSLMPWVVAT GDDDGTVKLW
     DPRKRDSVKT YTQHFDYISD FLWLDDKKQL VATSGDGTLS VMDVRAKEPK VVAQSEDQED
     DLLSIVAIKS AQKILVGTQL GILSVFNRKK GWGDCVDRIP GHPLSIDTLC NIPDDIPDTD
     PTSTVLTGSS DGFVRVVQIL PTKFLGVVAD HGEFPVERIA VGGGRYWVGS VGHDEVLRMT
     DLGAFFHENH VDSDEEEDDE EEWGGIEGAD GSEGEEDEEG KAVEGSAEKG GGASSDESDD
     EDEEMEPQLG DQSSKRKRQP EVELPDPSRK SKKGKKETVI DKDFFDGL