ID   JIP5_DEBHA              Reviewed;         582 AA.
AC   Q6BWJ5;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 2.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=WD repeat-containing protein JIP5;
GN   Name=JIP5; OrderedLocusNames=DEHA2B10824g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
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DR   EMBL; CR382134; CAG85428.2; -; Genomic_DNA.
DR   RefSeq; XP_457424.2; XM_457424.1.
DR   AlphaFoldDB; Q6BWJ5; -.
DR   SMR; Q6BWJ5; -.
DR   STRING; 4959.XP_457424.2; -.
DR   PRIDE; Q6BWJ5; -.
DR   EnsemblFungi; CAG85428; CAG85428; DEHA2B10824g.
DR   GeneID; 2913355; -.
DR   KEGG; dha:DEHA2B10824g; -.
DR   VEuPathDB; FungiDB:DEHA2B10824g; -.
DR   eggNOG; KOG2444; Eukaryota.
DR   HOGENOM; CLU_035623_0_0_1; -.
DR   InParanoid; Q6BWJ5; -.
DR   OMA; TRIKVNK; -.
DR   OrthoDB; 676458at2759; -.
DR   Proteomes; UP000000599; Chromosome B.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..582
FT                   /note="WD repeat-containing protein JIP5"
FT                   /id="PRO_0000333558"
FT   REPEAT          27..68
FT                   /note="WD 1"
FT   REPEAT          125..168
FT                   /note="WD 2"
FT   REPEAT          177..216
FT                   /note="WD 3"
FT   REPEAT          265..310
FT                   /note="WD 4"
FT   REPEAT          373..410
FT                   /note="WD 5"
FT   REGION          405..496
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          531..582
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        408..441
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        451..482
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        531..556
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        566..582
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   582 AA;  64919 MW;  77E51497C9D7404E CRC64;
     MAKKKKSNAT NAARLLESSI SPIVEIKYPE PLFTIAAHPT KPILLSGLAT GHIYCSTYDA
     DILEEAQSTK REKLSLLEKE AFKTGKIAHI NRSVSQSKQK WWTVIEDNAD IPDGSNIVNN
     WKTKRHKGSC RSAIFDPLEN SLGENIYSVG TDHIIKKANT ETGKVLSKAT ISEHYSDKND
     AITKLVHSTS HPFLLSGTEN GDVLVYDSNN MASNQLKFNV SKAHDDSINH ILPMPAVSAY
     HYLTLGSTTL SHIDIRKGII TQSDDQEDEL LSMCFASDHV NDNKNDTVLV SHGEGIVTIW
     KNSKNRLMDQ LSRIKVNKEA SIDAIIPTMN CDDGEMVDSV WCGDSEGLLH RINYKKGKVV
     ETRVHSSAAG KHGPADEVGI LDIDYDYRLI SAGMDSLKIW SNQEETLNSD SDDSDSDDSD
     SDIGSNDSED SDSDDDDVAI NNKIEDEVND FSPDSDSETG NDDSDENLED VADSDSNEDQ
     IENVTDEEHQ LSDTELPTKS LQIIRKKRFN VPEISNKTNI NKKVVDINKL TKEQSTKKAD
     EEPEETEEPD KKKQKLKAKQ MSTKQIRNMQ KHEHGIRRFD DL