ID   JIP5_LODEL              Reviewed;         584 AA.
AC   A5DSU5;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=WD repeat-containing protein JIP5;
GN   Name=JIP5; ORFNames=LELG_00431;
OS   Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS   1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC   Lodderomyces.
OX   NCBI_TaxID=379508;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL
RC   YB-4239;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
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DR   EMBL; CH981524; EDK42253.1; -; Genomic_DNA.
DR   RefSeq; XP_001527911.1; XM_001527861.1.
DR   AlphaFoldDB; A5DSU5; -.
DR   SMR; A5DSU5; -.
DR   STRING; 379508.A5DSU5; -.
DR   EnsemblFungi; EDK42253; EDK42253; LELG_00431.
DR   GeneID; 5235894; -.
DR   KEGG; lel:LELG_00431; -.
DR   VEuPathDB; FungiDB:LELG_00431; -.
DR   eggNOG; KOG2444; Eukaryota.
DR   HOGENOM; CLU_035623_0_0_1; -.
DR   InParanoid; A5DSU5; -.
DR   OMA; TRIKVNK; -.
DR   OrthoDB; 676458at2759; -.
DR   Proteomes; UP000001996; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SMART; SM00320; WD40; 4.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..584
FT                   /note="WD repeat-containing protein JIP5"
FT                   /id="PRO_0000333562"
FT   REPEAT          128..173
FT                   /note="WD 1"
FT   REPEAT          180..219
FT                   /note="WD 2"
FT   REPEAT          269..314
FT                   /note="WD 3"
FT   REPEAT          378..415
FT                   /note="WD 4"
FT   REGION          409..497
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          516..563
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        411..434
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        444..476
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        477..497
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   584 AA;  65777 MW;  3630D4CD8437C58C CRC64;
     MGKKKNNSSN AAHVLESSVA PILELNFTDP LFTTAAHPTK PLLISGFATG HLYCNSYNGE
     KLEELEQVNR EKAIERQQKA YEAGTITHVN KSVSQLKSKW WTTFNDIKDV PSKGEELVNV
     QTNWKTKRHK GSCRHAIFDP RTDCLGDYLY TCGTDNIIKK AATETGKVVG KVDVVADYSS
     AKDKLTKLCH STTHPFLLSG TEDGHVLVYD SSNLGGTNKI KFKVELAHDD SINHILSMPA
     VSPYHYLTLG STTLSHIDIR KGIITQSDDQ EDELLAMSYT TDELSENKND TVLVSHGEGI
     ITIWKNSKNK LADQLTRIKV NKTASIDAIV PTMNNDDENG MASSVWCGDS EGLLHRVNYK
     RGRVVETRLH SVARGKSDAV DEVGVLDIDY DYRLISAGMD SLKIWSNRYS DDQEEEEEEE
     EEEEEEEDSV SGTDSGSDEE SFSDISSVDF DSENNDDGEE LLDKEQWEDV EDEDIPVGTD
     GSTRNEENKD NTKSEYILPF KRKRRDFSEV ITKPKKKLID INKLTKPSKK EDDGDDNNKS
     LQEQEKAEEV PQFKKQKVKE KKVTAKQLRN MQKHEHGIRK FEGL