ID   JIP5_NEUCR              Reviewed;         421 AA.
AC   Q7S4F7; V5IKJ8;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   25-MAY-2022, entry version 116.
DE   RecName: Full=WD repeat-containing protein jip5;
GN   Name=jip5; ORFNames=NCU06021;
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA   Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA   Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA   Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA   Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA   Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA   Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
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DR   EMBL; CM002242; ESA41931.1; -; Genomic_DNA.
DR   EMBL; CM002242; ESA41932.1; -; Genomic_DNA.
DR   EMBL; CM002242; ESA41933.1; -; Genomic_DNA.
DR   RefSeq; XP_011395217.1; XM_011396915.1.
DR   RefSeq; XP_011395218.1; XM_011396916.1.
DR   RefSeq; XP_011395219.1; XM_011396917.1.
DR   AlphaFoldDB; Q7S4F7; -.
DR   SMR; Q7S4F7; -.
DR   STRING; 5141.EFNCRP00000005299; -.
DR   EnsemblFungi; ESA41931; ESA41931; NCU06021.
DR   EnsemblFungi; ESA41932; ESA41932; NCU06021.
DR   EnsemblFungi; ESA41933; ESA41933; NCU06021.
DR   GeneID; 3875770; -.
DR   KEGG; ncr:NCU06021; -.
DR   VEuPathDB; FungiDB:NCU06021; -.
DR   HOGENOM; CLU_052691_0_0_1; -.
DR   InParanoid; Q7S4F7; -.
DR   OMA; QTHHPHD; -.
DR   Proteomes; UP000001805; Chromosome 7, Linkage Group VII.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SMART; SM00320; WD40; 3.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..421
FT                   /note="WD repeat-containing protein jip5"
FT                   /id="PRO_0000333566"
FT   REPEAT          9..48
FT                   /note="WD 1"
FT   REPEAT          71..110
FT                   /note="WD 2"
FT   REPEAT          120..159
FT                   /note="WD 3"
FT   REPEAT          220..263
FT                   /note="WD 4"
FT   REPEAT          277..317
FT                   /note="WD 5"
FT   REPEAT          321..358
FT                   /note="WD 6"
FT   REGION          39..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          351..421
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        395..409
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   421 AA;  45353 MW;  F522CF541A9F37E5 CRC64;
     MLENLCTLPL SADLFTQVVH PSKPLLTVGL SNGRVETFRI PTNEDSDDDE DENSSITGGK
     GVIKSVWSTH RHKGSCRTLT YSTDGESLYS AGTDSIVKHF SPETGVVISK IGLPPVNSTS
     SQSDTPAILH TLSPQTLLLG TDSGSLYIFD LRENGSLNPK PVRKHVPHSD YISSLTPLPP
     SSESTSGFPK QWVSTGGATL AVTDLRHGIM ATSEDQEDEL LCSTVIPTGL GPKHMRNNAV
     LAVGTGGGVL TLWDRGAWDD QQERIYVAPG ETKRDGESLD AIVRVPDELG WGKKAVVGVG
     DGTVKIVDLK RREVQTTFQH DEVEGVAALN FDYENRLISG GGRTVKVWAE AGSAQEDEEE
     EEEVVEADQG VKRPAGSDDS DDDDGSDSDS DRPKRERKKK RRKGNKKGKH GGPSVSFPGL
     D