ID   JIP5_PICGU              Reviewed;         490 AA.
AC   A5DEK6;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 2.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=WD repeat-containing protein JIP5;
GN   Name=JIP5; ORFNames=PGUG_01707;
OS   Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS   / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX   NCBI_TaxID=294746;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
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DR   EMBL; CH408156; EDK37609.2; -; Genomic_DNA.
DR   RefSeq; XP_001486036.1; XM_001485986.1.
DR   AlphaFoldDB; A5DEK6; -.
DR   SMR; A5DEK6; -.
DR   STRING; 4929.XP_001486036.1; -.
DR   EnsemblFungi; EDK37609; EDK37609; PGUG_01707.
DR   GeneID; 5127538; -.
DR   KEGG; pgu:PGUG_01707; -.
DR   VEuPathDB; FungiDB:PGUG_01707; -.
DR   eggNOG; KOG2444; Eukaryota.
DR   HOGENOM; CLU_035623_0_0_1; -.
DR   InParanoid; A5DEK6; -.
DR   OMA; QTHHPHD; -.
DR   OrthoDB; 676458at2759; -.
DR   Proteomes; UP000001997; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..490
FT                   /note="WD repeat-containing protein JIP5"
FT                   /id="PRO_0000333568"
FT   REPEAT          23..64
FT                   /note="WD 1"
FT   REPEAT          70..112
FT                   /note="WD 2"
FT   REPEAT          118..155
FT                   /note="WD 3"
FT   REPEAT          157..196
FT                   /note="WD 4"
FT   REPEAT          242..284
FT                   /note="WD 5"
FT   REPEAT          286..327
FT                   /note="WD 6"
FT   REPEAT          340..377
FT                   /note="WD 7"
FT   REGION          368..490
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        369..434
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        435..449
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        450..465
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   490 AA;  54352 MW;  5F2DADEAD01BAE74 CRC64;
     MAKKAKKDGR SVEPTGNPIL EVKYNDPLFS IAAHPTEPIF VSGLATGHVF CNRYDAERLE
     ERMQAIKDEQ KKKSKTSVKT TNAAWWTQVE DITNTDEIVT CWKTKRHKGS CRSVLFDPIE
     SSVGKHLFTV GKDHVVKKAN TETGKVLTKT DISKDLSSKD AVTKLCHSTT HPFLLSGTEN
     GHVLVYDSND LSNKFKVENV HEDAVNHILA MPSVSPYHYL TVGSTTLSHI DIRKGIVTQS
     DDQEDELLSM SFVPDDDRND TVLVSHGGGI VTIWKNSKNK LMDQLSRIKV NKEASIDVMI
     SAMDAGDDDM AASVWCGDSD GLVHRVNYKK GKVVETRLHG TADEVGFLDI DYEYRLLTAG
     MDSMKLWSAE GDDEEEEESE GEESEESEES DEESDESSGE ESEGDDGNGS NSEESDSNDE
     DEVESSDDEK EKEEESTETD HKNIEAESGK QANKRQASQP KSAGENVKKQ KLKQTSKLAH
     SHGIRRFDGL