ID   JIP5_PICST              Reviewed;         533 AA.
AC   A3LPR4;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 2.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=WD repeat-containing protein JIP5;
GN   Name=JIP5; ORFNames=PICST_54913;
OS   Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS   Y-11545) (Yeast) (Pichia stipitis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX   NCBI_TaxID=322104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX   PubMed=17334359; DOI=10.1038/nbt1290;
RA   Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA   Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA   Passoth V., Richardson P.M.;
RT   "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT   yeast Pichia stipitis.";
RL   Nat. Biotechnol. 25:319-326(2007).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
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DR   EMBL; CP000496; ABN65087.2; -; Genomic_DNA.
DR   RefSeq; XP_001383116.2; XM_001383079.1.
DR   AlphaFoldDB; A3LPR4; -.
DR   SMR; A3LPR4; -.
DR   STRING; 4924.XP_001383116.2; -.
DR   EnsemblFungi; ABN65087; ABN65087; PICST_54913.
DR   GeneID; 4836748; -.
DR   KEGG; pic:PICST_54913; -.
DR   eggNOG; KOG2444; Eukaryota.
DR   HOGENOM; CLU_035623_0_0_1; -.
DR   InParanoid; A3LPR4; -.
DR   OMA; TRIKVNK; -.
DR   OrthoDB; 676458at2759; -.
DR   Proteomes; UP000002258; Chromosome 2.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..533
FT                   /note="WD repeat-containing protein JIP5"
FT                   /id="PRO_0000333569"
FT   REPEAT          26..67
FT                   /note="WD 1"
FT   REPEAT          84..130
FT                   /note="WD 2"
FT   REPEAT          176..215
FT                   /note="WD 3"
FT   REPEAT          264..309
FT                   /note="WD 4"
FT   REPEAT          372..409
FT                   /note="WD 5"
FT   REGION          408..533
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        408..425
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        451..465
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        478..533
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   533 AA;  59311 MW;  A73B03D0E562AF57 CRC64;
     MKKRKSNAVN AAQVLESSVS PILEINYSDP LFTLAAHPTE PVLISGLVTG HVFCHRYDAE
     ALEEKQSARR EQLLLQEKEA FKKGKVSQIS KSVSQSKNPW WTIIKDHTEV PQESGVVASW
     KTKRHKGSCR HAIFEPLESS VGENIFTVGT DHIIKKASSE TGKVVGKVDV SLDFPNSNDS
     ITKLCHSATN SCLLAGTENG HVLVYDSKNL GGSKLKYKVS SAHDDAVNHI LAMPAVSAYH
     YLTLGSTTLS HIDIRKGIIT QSDNQDDELL SMCFATDQIN DGKNDTVLVG HGEGIVTIWK
     NSKNRFMDQL TRIKVNKEAS IDAIIPTMNC DDDEMAASVW CGDSEGLLHR VNYKKGKVVE
     TRVHSSSRGK YGAADEVGLL EIDYDYRLIS AGMESLKIWS NEQNEEIALD ESDDSDDESD
     SDNSEDDLSS GSLSDTASDE EIEENKEEED EKEDKPVKID HPLANRSKKG LVGVSKHVTK
     KKQIDINKLT KKGKEEEEEE QPQKKKPKKD QLSTKQLRNM QKHEHGIRRF DDL