ID   JIP5_VANPO              Reviewed;         559 AA.
AC   A7TH93;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=WD repeat-containing protein JIP5;
GN   Name=JIP5; ORFNames=Kpol_1013p46;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
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DR   EMBL; DS480390; EDO18374.1; -; Genomic_DNA.
DR   RefSeq; XP_001646232.1; XM_001646182.1.
DR   AlphaFoldDB; A7TH93; -.
DR   SMR; A7TH93; -.
DR   STRING; 436907.A7TH93; -.
DR   EnsemblFungi; EDO18374; EDO18374; Kpol_1013p46.
DR   GeneID; 5546658; -.
DR   KEGG; vpo:Kpol_1013p46; -.
DR   eggNOG; KOG2444; Eukaryota.
DR   HOGENOM; CLU_035623_0_0_1; -.
DR   InParanoid; A7TH93; -.
DR   OMA; TRIKVNK; -.
DR   OrthoDB; 1173229at2759; -.
DR   PhylomeDB; A7TH93; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SMART; SM00320; WD40; 4.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..559
FT                   /note="WD repeat-containing protein JIP5"
FT                   /id="PRO_0000333573"
FT   REPEAT          26..67
FT                   /note="WD 1"
FT   REPEAT          77..116
FT                   /note="WD 2"
FT   REPEAT          117..156
FT                   /note="WD 3"
FT   REPEAT          162..201
FT                   /note="WD 4"
FT   REPEAT          207..247
FT                   /note="WD 5"
FT   REPEAT          265..306
FT                   /note="WD 6"
FT   REPEAT          313..347
FT                   /note="WD 7"
FT   REPEAT          354..394
FT                   /note="WD 8"
FT   REPEAT          428..470
FT                   /note="WD 9"
FT   REGION          386..500
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          515..559
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        390..415
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        443..461
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        536..559
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   559 AA;  62472 MW;  5E8E644432F60FD4 CRC64;
     MGKKNKSKIN PIEELKSDCL PILELQYSDP LFQIASHPEQ AIIISGLATG YVYCHRYNVT
     VLENYLQQQK KKFVSDADGK KSKKVKFWTV YDIINENKDN ADTGSDSGVE LIWKTKRHKG
     SVRCIALDSD GQFVYTVGTD NVLKKADVLT GKVVKKTNLK NDNGGKYTKM VKSPTHSLLI
     LGDENGTVIV LNSETLQETN RLTKVHNGDD AINDIFHFAK RSIYRYISLG QTTLAYWDAR
     ESNESDFKLD PEDTTSKRKV MLSDDQEDEV LCGTFVDPEV GDNLVCGMGD GILTVWKPER
     NDLEDQLNRI KIAKEESIDC IVPTLQDDNC IWCGCSNGNI YKADIKKGKV VEVRNHSSLD
     EVSFLDLDYD YRVISGGMDK VKIWQSRNEV SEEEDDEESE SFSDSDSDSD SDSDSDSDSD
     RDRDRDSDSD GDSDGDDIGN GSDVNDSGAS GSENDSSDVW EGLENGSDDE PVQEKDETSG
     SDMDDIDEGS DSSEGELIGL SREELIAELD EDIMEESEQE GEKLQKKRKN EPSKKNTKNL
     KKVKPSYNDS HGIRKFEGL