ID   JIP5_YEAS7              Reviewed;         492 AA.
AC   A6ZX45;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 2.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=WD repeat-containing protein JIP5;
DE   AltName: Full=Jumonji domain-interacting protein 5;
GN   Name=JIP5; ORFNames=SCY_5872;
OS   Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=307796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJM789;
RX   PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA   Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA   Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA   Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA   Steinmetz L.M.;
RT   "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT   strain YJM789.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC   -!- SUBUNIT: Interacts with BRE1, BUD27 and GIS1.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EDN61287.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AAFW02000135; EDN61287.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; A6ZX45; -.
DR   SMR; A6ZX45; -.
DR   EnsemblFungi; EDN61287; EDN61287; SCY_5872.
DR   HOGENOM; CLU_035623_0_0_1; -.
DR   Proteomes; UP000007060; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Nucleus; Repeat; WD repeat.
FT   CHAIN           1..492
FT                   /note="WD repeat-containing protein JIP5"
FT                   /id="PRO_0000333543"
FT   REPEAT          127..166
FT                   /note="WD 1"
FT   REPEAT          178..217
FT                   /note="WD 2"
FT   REPEAT          236..274
FT                   /note="WD 3"
FT   REPEAT          276..317
FT                   /note="WD 4"
FT   REPEAT          365..405
FT                   /note="WD 5"
FT   REGION          404..472
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        404..429
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        435..472
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   492 AA;  55252 MW;  75964BD4408EB9B9 CRC64;
     MAKSKKKTDV VDSTNLPILE LLSLKAPIFQ SLLHPELPII ITGFGTGHIV CHRYDPAKLQ
     SHLDRRRRID TATTGKDAKK GVCPWIRLDI DLETGDLKLV DIEEQHQQKQ TGKDEDLGVK
     TLWKTKRHKG SVRAMCFDSK GDNIFSVGSD NVLKKANTMT GKVVKKVNLS SLFNSEEKKN
     DKFTKLCASQ THPFILIGDE SGNIHVINSE NLALSNSIRS IHFGDSINDI FHFDKRSAYK
     FISLGQTTLA YFDVRDKDAK PNVAGNEDGK ILISDDQEDE VLCGCFVDPE VADTLLCGMG
     EGIVTVWKPN KNDLEDQMSR IKISKDESID CIVPTLQDDN CVWCGCSNGN IYKVNAKLGK
     VVEVRNHNEL DEVSFVDLDF EYRVVSGGLE NIKIWELSSD DVEENASVES DSDEPLSHSD
     EDLSDDTSSD DETTLVGLSK EELLDELDKD LKEDHQEEKE SNSKSVKKRK IMKENNKKKD
     LYEHGIKKFD DL