ID   JJJ2_KLULA              Reviewed;         653 AA.
AC   Q6CW35;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=J protein JJJ2;
GN   Name=JJJ2; OrderedLocusNames=KLLA0B07271g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR382122; CAH02247.1; -; Genomic_DNA.
DR   RefSeq; XP_451854.1; XM_451854.1.
DR   AlphaFoldDB; Q6CW35; -.
DR   SMR; Q6CW35; -.
DR   STRING; 28985.XP_451854.1; -.
DR   EnsemblFungi; CAH02247; CAH02247; KLLA0_B07271g.
DR   GeneID; 2897123; -.
DR   KEGG; kla:KLLA0_B07271g; -.
DR   eggNOG; KOG0714; Eukaryota.
DR   HOGENOM; CLU_490950_0_0_1; -.
DR   InParanoid; Q6CW35; -.
DR   OMA; ARSKFEC; -.
DR   Proteomes; UP000000598; Chromosome B.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0030544; F:Hsp70 protein binding; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   CDD; cd06257; DnaJ; 1.
DR   Gene3D; 1.10.287.110; -; 1.
DR   InterPro; IPR001623; DnaJ_domain.
DR   InterPro; IPR044713; DNJA1/2-like.
DR   InterPro; IPR036869; J_dom_sf.
DR   PANTHER; PTHR43888; PTHR43888; 1.
DR   Pfam; PF00226; DnaJ; 1.
DR   PRINTS; PR00625; JDOMAIN.
DR   SMART; SM00271; DnaJ; 1.
DR   SUPFAM; SSF46565; SSF46565; 1.
DR   PROSITE; PS50076; DNAJ_2; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..653
FT                   /note="J protein JJJ2"
FT                   /id="PRO_0000333577"
FT   DOMAIN          14..78
FT                   /note="J"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00286"
FT   REGION          85..308
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          490..512
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        91..120
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        121..135
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        157..243
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        294..308
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        495..512
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   653 AA;  73816 MW;  E468DCFC73CDDB73 CRC64;
     MSGSDKTYQL DETTLYSVLN LKYGATEVQI RKAYMKLARE LHPDKSKSEE AGELFKKVAH
     AHFILTDKKE KMKYDSKLLA KGLYDYSPRI PNDKSRQNGM FKDTAKNSKT FTNNNNKDDA
     SADTSKSKPR KSRPYEEQPY GFGVDTGRGS GKNIPLFKTF NAKSYQNSKK SVTPPRPKQP
     SEKNKRATSF SNENRNSSSV PLAKNQAKKT ANSGSAVGSE SRISSSGSES SSNVNSATGS
     SEEPDVHTQH KMARKDSYLS GFQSKARSPE SPFQDPAQRH FVRTKYVSSR YDKRSLSPVK
     TTPNSSTETL NNVKNIFNSM SDRLRHTLFG NSNGDAEDED QHNTQHDTER LFKRAKLPGR
     KILTDEEIDE IVKQQNEAES NDPDRQDYGN SFNLNVDNLS VNTQDFNHIS EPSPEKEETK
     ANKAPFLEEV YEIKSDNEHL EEKAAVSPDD GIDTLGLNEL GETLPNNKEP FDMRNVGDSL
     DNYQVKRMKV SPKPRSVPSK TTPGSSHAEE NLQEPVNIPL PRIYKLDPIP IEKFNVDLSI
     SNIKLPEMPN LLCNVLDKAQ VLECQQKTAE FTKQTNETKR KLLHILSQRC SADEELHDKL
     YRVENVNRMV EAKLYDLELM TKLSELLNRQ RMVAENYAIM INTMYASGLL EKN