ID   JUNB_CYPCA              Reviewed;         308 AA.
AC   P79703;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Transcription factor JunB {ECO:0000305};
DE   AltName: Full=Transcription factor AP-1 subunit JunB {ECO:0000305};
GN   Name=junb;
OS   Cyprinus carpio (Common carp).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Cyprininae; Cyprinus.
OX   NCBI_TaxID=7962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Chang M.S., Huang C.J.;
RL   Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcription factor involved in regulating gene activity
CC       following the primary growth factor response. Binds to the DNA sequence
CC       5'-TGA[CG]TCA-3' (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Binds DNA as a homodimer or as a heterodimer with another
CC       member of the jun/fos family.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- SIMILARITY: Belongs to the bZIP family. Jun subfamily. {ECO:0000305}.
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DR   EMBL; U81506; AAB39939.1; -; mRNA.
DR   AlphaFoldDB; P79703; -.
DR   SMR; P79703; -.
DR   Proteomes; UP000694384; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   InterPro; IPR004827; bZIP.
DR   InterPro; IPR046347; bZIP_sf.
DR   InterPro; IPR005643; JNK.
DR   InterPro; IPR029822; JunB.
DR   InterPro; IPR002112; Leuzip_Jun.
DR   InterPro; IPR008917; TF_DNA-bd_sf.
DR   PANTHER; PTHR11462:SF37; PTHR11462:SF37; 1.
DR   Pfam; PF00170; bZIP_1; 1.
DR   Pfam; PF03957; Jun; 1.
DR   PRINTS; PR00043; LEUZIPPRJUN.
DR   SMART; SM00338; BRLZ; 1.
DR   SUPFAM; SSF47454; SSF47454; 1.
DR   SUPFAM; SSF57959; SSF57959; 1.
DR   PROSITE; PS50217; BZIP; 1.
DR   PROSITE; PS00036; BZIP_BASIC; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..308
FT                   /note="Transcription factor JunB"
FT                   /id="PRO_0000076441"
FT   DOMAIN          229..292
FT                   /note="bZIP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT   REGION          229..256
FT                   /note="Basic motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT   REGION          257..285
FT                   /note="Leucine-zipper"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
SQ   SEQUENCE   308 AA;  34370 MW;  3A5739807457353D CRC64;
     MSTKMEQPFY HDDSFLVGYG HNDAALHDYK LQKQSMNLNL TEPYRNLKSD LYHTSGADSG
     SLKLASPELE RLIIQTSNGV LTTPTPGQYL YSRGITDEQE GFAEGFVKAL DDLHKMFQMP
     PPNVSIGAGG VTTCSTTASV FGSSLQSEPP IYTLNAYCPA PSHPSTTISY LPPHVQQSQH
     PENTHGFQHS GVLPQRYVPL KEEPQTVPDM HSSDCSPPTS PIDMENQERI KAERKRLRNR
     LAATKCRKRK LERISRLEEK VKVLKNDNAG LSNTASVLRD QVAQLKQKVL RHMNSGCQLM
     LTSKMEAF