ID   50511_ASFB7             Reviewed;         542 AA.
AC   Q65208;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   23-FEB-2022, entry version 67.
DE   RecName: Full=Protein MGF 505-11L;
GN   OrderedLocusNames=BA71V-150; ORFNames=DP542L;
OS   African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS   (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10498;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA   Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA   Rodriguez J.F., Vinuela E.;
RT   "Analysis of the complete nucleotide sequence of African swine fever
RT   virus.";
RL   Virology 208:249-278(1995).
RN   [2]
RP   FUNCTION.
RX   PubMed=11238833; DOI=10.1128/jvi.75.7.3066-3076.2001;
RA   Zsak L., Lu Z., Burrage T.G., Neilan J.G., Kutish G.F., Moore D.M.,
RA   Rock D.L.;
RT   "African swine fever virus multigene family 360 and 530 genes are novel
RT   macrophage host range determinants.";
RL   J. Virol. 75:3066-3076(2001).
RN   [3]
RP   INDUCTION.
RX   PubMed=32075923; DOI=10.1128/jvi.00119-20;
RA   Cackett G., Matelska D., Sykora M., Portugal R., Malecki M., Baehler J.,
RA   Dixon L., Werner F.;
RT   "The African Swine Fever Virus Transcriptome.";
RL   J. Virol. 94:0-0(2020).
CC   -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC       efficient virus replication in macrophages.
CC       {ECO:0000269|PubMed:11238833}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       {ECO:0000269|PubMed:32075923}.
CC   -!- SIMILARITY: Belongs to the asfivirus MGF 505 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U18466; AAA65376.1; -; Genomic_DNA.
DR   RefSeq; NP_042840.1; NC_001659.2.
DR   SMR; Q65208; -.
DR   GeneID; 22220376; -.
DR   KEGG; vg:22220376; -.
DR   Proteomes; UP000000624; Genome.
DR   InterPro; IPR004858; MGF_505.
DR   Pfam; PF03158; DUF249; 1.
PE   2: Evidence at transcript level;
KW   Early protein; Reference proteome.
FT   CHAIN           1..542
FT                   /note="Protein MGF 505-11L"
FT                   /id="PRO_0000373354"
SQ   SEQUENCE   542 AA;  63354 MW;  B17FBD1C71F68109 CRC64;
     MFSLQKKALQ HIYMTPENAS QLTKDLLQHL GLYWNGPVIK MDTVVHLHNK IFSNRSVLKY
     ALAKQANITI IKTLVLWVEP EYALAQALKH NRKDVLECIF SYHLTTPKYH HIMHLTSSQE
     LFEFFHLFIC KSKNYNARME CLLYAATLYN FPNILEKNRE YIIRHSIGNT LFAIACKERH
     IHLIAWFVTA GVLDTYDDST LFNTAFRLGD YSLLEVACDL PIIYPDYLII SMMQTAIQKN
     YFRFFKKLLT HFNIYRQIII TDAAYYNRRK ILLLLLNQNV FNNFAILCAL SAAIKGHASK
     KTLNLLISQL DSQMTVIDSV YYSIIKYNNI DCIPLLMQIK TFRLETLVSI AVHGDNIDII
     AACKAFLPKD TLYHLVLKMA IISRNHKLFK LYTEKENPMY IFTTIKAIIS NLVNYTVVQA
     VAIEYLREFH REKQLPIVPL LMVLAEHNYI TKFKKACYAA NMSDQKVKRA LIKCLFIASQ
     KNYCQIFKYC FGSLLKVLSK HERVKFFNSV VFAKKLASYY DHQNMIHLID SLIERFRYLI
     KD