JZT68_CHIGU
ID JZT68_CHIGU Reviewed; 50 AA.
AC B1P1I8;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 29-APR-2008, sequence version 1.
DT 25-MAY-2022, entry version 22.
DE RecName: Full=U37-theraphotoxin-Cg1b;
DE Short=U37-TRTX-Cg1b;
DE AltName: Full=Jingzhaotoxin-like peptide JZTX-68 {ECO:0000312|EMBL:ABY71738.1};
DE Short=JZTX-68 {ECO:0000312|EMBL:ABY71738.1};
DE Flags: Precursor;
OS Chilobrachys guangxiensis (Chinese earth tiger tarantula) (Chilobrachys
OS jingzhao).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC Mygalomorphae; Theraphosidae; Chilobrachys.
OX NCBI_TaxID=278060;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Venom gland;
RX PubMed=18581053; DOI=10.1007/s00018-008-8135-x;
RA Chen J., Deng M., He Q., Meng E., Jiang L., Liao Z., Rong M., Liang S.;
RT "Molecular diversity and evolution of cystine knot toxins of the tarantula
RT Chilobrachys jingzhao.";
RL Cell. Mol. Life Sci. 65:2431-2444(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC -!- SIMILARITY: Belongs to the neurotoxin 10 (Hwtx-1) family. 67 (Jztx-67)
CC subfamily. {ECO:0000305}.
CC -!- CAUTION: Lacks the C-terminal part containing the 'disulfide through
CC disulfide knot' structure. {ECO:0000305}.
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DR EMBL; EU233919; ABY71738.1; -; mRNA.
DR AlphaFoldDB; B1P1I8; -.
DR ArachnoServer; AS000867; U37-theraphotoxin-Cg1b.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 2: Evidence at transcript level;
KW Secreted; Signal; Toxin.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT PEPTIDE 20..50
FT /note="U37-theraphotoxin-Cg1b"
FT /id="PRO_0000398551"
SQ SEQUENCE 50 AA; 5565 MW; 9F30AA78AEB536A7 CRC64;
MRVLLIIAGL ALLSVVCYTS EMKEQNSLNE VLSAFFDVEE PPEKGCIICF