K0513_MOUSE
ID K0513_MOUSE Reviewed; 407 AA.
AC Q8R0A7; Q80TY8; Q8BQV3; Q8C8N9; Q8CCN0;
DT 13-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Uncharacterized protein KIAA0513;
GN Name=Kiaa0513;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=12693553; DOI=10.1093/dnares/10.1.35;
RA Okazaki N., Kikuno R., Ohara R., Inamoto S., Aizawa H., Yuasa S.,
RA Nakajima D., Nagase T., Ohara O., Koga H.;
RT "Prediction of the coding sequences of mouse homologues of KIAA gene: II.
RT The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs
RT identified by screening of terminal sequences of cDNA clones randomly
RT sampled from size-fractionated libraries.";
RL DNA Res. 10:35-48(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Corpora quadrigemina, Olfactory bulb, and Retina;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Eye;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-275, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Lung, Pancreas, and Spleen;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC65581.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AK122299; BAC65581.1; ALT_INIT; mRNA.
DR EMBL; AK032447; BAC27873.1; -; mRNA.
DR EMBL; AK044754; BAC32067.1; -; mRNA.
DR EMBL; AK046401; BAC32707.1; -; mRNA.
DR EMBL; BC027126; AAH27126.1; -; mRNA.
DR CCDS; CCDS22716.1; -.
DR RefSeq; NP_001157232.1; NM_001163760.1.
DR RefSeq; NP_001157233.1; NM_001163761.1.
DR RefSeq; NP_758490.3; NM_172286.4.
DR RefSeq; XP_006530997.1; XM_006530934.2.
DR AlphaFoldDB; Q8R0A7; -.
DR BioGRID; 231581; 3.
DR STRING; 10090.ENSMUSP00000034281; -.
DR iPTMnet; Q8R0A7; -.
DR PhosphoSitePlus; Q8R0A7; -.
DR SwissPalm; Q8R0A7; -.
DR jPOST; Q8R0A7; -.
DR MaxQB; Q8R0A7; -.
DR PaxDb; Q8R0A7; -.
DR PeptideAtlas; Q8R0A7; -.
DR PRIDE; Q8R0A7; -.
DR ProteomicsDB; 268917; -.
DR Antibodypedia; 2867; 113 antibodies from 20 providers.
DR DNASU; 234797; -.
DR Ensembl; ENSMUST00000034281; ENSMUSP00000034281; ENSMUSG00000031824.
DR Ensembl; ENSMUST00000108950; ENSMUSP00000104578; ENSMUSG00000031824.
DR GeneID; 234797; -.
DR KEGG; mmu:234797; -.
DR UCSC; uc009nqt.1; mouse.
DR MGI; MGI:2443793; 6430548M08Rik.
DR VEuPathDB; HostDB:ENSMUSG00000031824; -.
DR eggNOG; ENOG502QV4D; Eukaryota.
DR GeneTree; ENSGT00390000009535; -.
DR InParanoid; Q8R0A7; -.
DR OMA; VREKWCH; -.
DR OrthoDB; 1417808at2759; -.
DR PhylomeDB; Q8R0A7; -.
DR TreeFam; TF325884; -.
DR BioGRID-ORCS; 234797; 3 hits in 70 CRISPR screens.
DR ChiTaRS; 6430548M08Rik; mouse.
DR PRO; PR:Q8R0A7; -.
DR Proteomes; UP000000589; Chromosome 8.
DR RNAct; Q8R0A7; protein.
DR Bgee; ENSMUSG00000031824; Expressed in retinal neural layer and 184 other tissues.
DR ExpressionAtlas; Q8R0A7; baseline and differential.
DR Genevisible; Q8R0A7; MM.
DR InterPro; IPR039872; KIAA0513.
DR PANTHER; PTHR13663; PTHR13663; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..407
FT /note="Uncharacterized protein KIAA0513"
FT /id="PRO_0000050758"
FT REGION 1..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..88
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 275
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT CONFLICT 78
FT /note="F -> I (in Ref. 2; BAC27873)"
FT /evidence="ECO:0000305"
FT CONFLICT 155
FT /note="F -> L (in Ref. 2; BAC32067)"
FT /evidence="ECO:0000305"
FT CONFLICT 198
FT /note="P -> T (in Ref. 2; BAC32707)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 407 AA; 46318 MW; 56DFB1DD3E6C933F CRC64;
MEAPEVPVGS LIDFETEPPT SPPLEAAPST LQDPDGSLGD GASESETTES ADSENDMGES
PSHPSWDQDR RSSSNESFSS NQSADSAPDE ETLALREFMR SYVEKIFSGG EDLDQEEKAK
FGEYCSGEDG KGREWFARFV SAQRCKSKCV SEPTFYRLVQ SFAVVLFECH QMDDFGPAKN
LMTMCFTYYH LGKPQLPPTE PREKPAGSID SYLKSANSWL AEKKDIAERL LKNTENMKGF
FGGLETKLKG PLVRKNEEDE NKPKDRQTKT VTMISPEDEQ KGEKVYLYTH LRQQPIWHTL
RFWNAAFFDA VHCERRKRSP TTRGDAGEQE EKREKWCHMT QEERDDSLRF NENITFGQLG
TFTHNMLAFG LNKKLCSDFL KKQAVIGNLD EEQYKLLSDH IEQMATE
