K0895_MOUSE
ID K0895_MOUSE Reviewed; 519 AA.
AC Q7TQE7; Q5DU11; Q80V66; Q9CTJ2;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 2.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Uncharacterized protein KIAA0895;
GN Name=Kiaa0895;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=C57BL/6J; TISSUE=Brain, and Thymus;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-510 (ISOFORM 1).
RC TISSUE=Fetal brain;
RA Okazaki N., Kikuno R.F., Ohara R., Inamoto S., Nagase T., Ohara O.,
RA Koga H.;
RT "Prediction of the coding sequences of mouse homologues of KIAA gene. The
RT complete nucleotide sequences of mouse KIAA-homologous cDNAs identified by
RT screening of terminal sequences of cDNA clones randomly sampled from size-
RT fractionated libraries.";
RL Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 436-519 (ISOFORMS 1/2).
RC STRAIN=C57BL/6J;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q7TQE7-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q7TQE7-2; Sequence=VSP_031688;
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD90420.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; BC039998; AAH39998.1; -; mRNA.
DR EMBL; BC054761; AAH54761.2; -; mRNA.
DR EMBL; AK220359; BAD90420.1; ALT_INIT; mRNA.
DR EMBL; AK003384; BAB22754.1; -; mRNA.
DR CCDS; CCDS40563.1; -. [Q7TQE7-1]
DR RefSeq; NP_081015.1; NM_026739.1. [Q7TQE7-1]
DR RefSeq; XP_006510636.1; XM_006510573.2. [Q7TQE7-2]
DR RefSeq; XP_011240894.1; XM_011242592.1. [Q7TQE7-2]
DR RefSeq; XP_017169037.1; XM_017313548.1. [Q7TQE7-2]
DR AlphaFoldDB; Q7TQE7; -.
DR BioGRID; 212785; 1.
DR STRING; 10090.ENSMUSP00000062120; -.
DR PhosphoSitePlus; Q7TQE7; -.
DR PaxDb; Q7TQE7; -.
DR PRIDE; Q7TQE7; -.
DR ProteomicsDB; 269039; -. [Q7TQE7-1]
DR ProteomicsDB; 269040; -. [Q7TQE7-2]
DR Antibodypedia; 66049; 24 antibodies from 11 providers.
DR DNASU; 68283; -.
DR Ensembl; ENSMUST00000058868; ENSMUSP00000062120; ENSMUSG00000036411. [Q7TQE7-1]
DR GeneID; 68283; -.
DR KEGG; mmu:68283; -.
DR UCSC; uc009oom.1; mouse. [Q7TQE7-1]
DR MGI; MGI:1915533; 9530077C05Rik.
DR VEuPathDB; HostDB:ENSMUSG00000036411; -.
DR eggNOG; ENOG502QQGI; Eukaryota.
DR GeneTree; ENSGT00390000004417; -.
DR HOGENOM; CLU_038689_1_0_1; -.
DR InParanoid; Q7TQE7; -.
DR OMA; THLLRMI; -.
DR OrthoDB; 749754at2759; -.
DR PhylomeDB; Q7TQE7; -.
DR TreeFam; TF329621; -.
DR BioGRID-ORCS; 68283; 0 hits in 71 CRISPR screens.
DR ChiTaRS; 9530077C05Rik; mouse.
DR PRO; PR:Q7TQE7; -.
DR Proteomes; UP000000589; Chromosome 9.
DR RNAct; Q7TQE7; protein.
DR Bgee; ENSMUSG00000036411; Expressed in spermatocyte and 110 other tissues.
DR ExpressionAtlas; Q7TQE7; baseline and differential.
DR Genevisible; Q7TQE7; MM.
DR InterPro; IPR012548; DUF1704.
DR PANTHER; PTHR31817; PTHR31817; 1.
DR Pfam; PF08014; DUF1704; 1.
DR SMART; SM01154; DUF1704; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..519
FT /note="Uncharacterized protein KIAA0895"
FT /id="PRO_0000320618"
FT REGION 63..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..99
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..244
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:15489334"
FT /id="VSP_031688"
SQ SEQUENCE 519 AA; 59404 MW; C54C69C17195D7A3 CRC64;
MLESIRVTEK LHWPEHELAK KFVLNAEEAL ITDSKRSFSS LSSGILKDTF TTGTSSYNVL
LQSKEEKKHR SQKRFSSASS KQHRKPSKSP SSSHSKDPSR MTALVPGTGA GTWYCLDGQS
AVFVTSSVPS PVKFTRDISI TGSGLALPPK PKSKVKRRNL TRLPKPKQQP QLCRSFERGD
DISGKKLCIL TAIKPINLEK EKLRFFKSDY TYNPQFEYAN PTLPGVLAKH SNASDRFLKQ
SINIMELTLQ KYGSYEKFEQ ATGGSLLSKT RIWSHVRKYM VKEGCLGEIV VHLTEDLLSR
ASMTVVNGCP TLTINISTAR EHWLEGMLRH EIGTHYFRGI NNLQQPWNSW IGRKKHELKP
NNPTEEGLAS IHSVLFRKDP FLWRAALLYY TVYKASHMSF CELFKDIGKF VKDPNTRWDY
CVRAKRGWTD TSEPGCFSKD QVYLDGVLQI LRFRESIDFH LLTALGKVSY EDVDRLKELA
VTENMRVPHF LHDHSRYMEH LERIMEVNEL TDAELKNLI
