K1522_DANRE
ID K1522_DANRE Reviewed; 1325 AA.
AC Q1LWM5;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2006, sequence version 1.
DT 03-AUG-2022, entry version 65.
DE RecName: Full=Uncharacterized protein KIAA1522 homolog;
GN ORFNames=si:ch211-194e15.5;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
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DR EMBL; BX547927; CAK04281.1; -; Genomic_DNA.
DR RefSeq; NP_001076559.1; NM_001083090.1.
DR AlphaFoldDB; Q1LWM5; -.
DR STRING; 7955.ENSDARP00000083006; -.
DR PaxDb; Q1LWM5; -.
DR Ensembl; ENSDART00000137633; ENSDARP00000120879; ENSDARG00000061804.
DR GeneID; 100034579; -.
DR KEGG; dre:100034579; -.
DR ZFIN; ZDB-GENE-060503-393; si:ch211-194e15.5.
DR eggNOG; ENOG502QV6M; Eukaryota.
DR GeneTree; ENSGT00950000182963; -.
DR HOGENOM; CLU_004158_0_0_1; -.
DR InParanoid; Q1LWM5; -.
DR OMA; PTNEGAP; -.
DR OrthoDB; 127180at2759; -.
DR PRO; PR:Q1LWM5; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 19.
DR Bgee; ENSDARG00000061804; Expressed in swim bladder and 18 other tissues.
DR GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
PE 4: Predicted;
KW Coiled coil; Reference proteome.
FT CHAIN 1..1325
FT /note="Uncharacterized protein KIAA1522 homolog"
FT /id="PRO_0000311248"
FT REGION 68..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 111..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 368..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 595..614
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 829..891
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 935..981
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1084..1138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1243..1272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1293..1313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 53..85
FT /evidence="ECO:0000255"
FT COMPBIAS 68..85
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 291..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..383
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 384..398
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..444
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 460..485
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..548
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 549..563
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 832..852
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1325 AA; 145305 MW; A1A074F9D11F92A1 CRC64;
MVVFLSKNVR SLLSIFKKKG QKQDEQRKLT VHYTASQHYQ ENVFIEGSRP KYLEDLHTEA
QEGLKILQQE EEDTSSKERN ESLENDSTSG HSIISVSTAS AVSTRPVLTR QGSTFKPLNP
VKRLDKSKRR SRRTTIMGIP QQVQRELDMA RGTMLQQLPN RGHDSEDDSS GTVVLQTIDG
DLPSVNHEGA RVHLQNIEVL QASRDEDLLL NHIHSVYQDE LNRKLGLGAC PTQRPKSLAV
PGMTTYSFLQ EPQGPVMSIS PQATYLSKII PNAVLPAAID IIEINHDHNR CSASTASKGS
MASASPSSSR SGSGTNQAPP TTSPSRSNSQ SSETIVSNSS TISSKGKCLP TFDADSAKDI
SVLIPKDMSV SSSSSWKSSE GKGTNHRLNP REYGDAGDNV RNSHSFSRSL SVMKTKLPPA
PPQRTYSLHH ENMQRQREQG DIQDPKDVAP NNNEQTNRDI SSTKENHQSA KNKKSSVHSL
ELRSDFHTTV KSSPLSPDQV FTGRHARSGN SSPQKTRECG ENFDRTLSPS SGYSSQSGTP
THSPKEVSPS SPGKRRVKPS KPERVCAKTS PVVSVSSSLT SLSSVISDTA HQDIQTNTTS
SEPLKFSPPL TTVKNKVTPT HQTIALRTLF NIPPPPKVKA PSPPPPETWV QNKQTLELLC
GPGPNIHKLE SLISKTQNKN SMQINEQVIP KTQTTEETKT ENTVVKELTK SASPQVHKQM
MVEPPDVRHT EKSILHNELK SPETLAKVNQ IPHTQDEKTI EDQKDRWSQT LPTTNVPSII
VDQSMLSQTN SIEKTKAATV SSNENQRNCI VTDIVNRISV QTLNIEVPEV NGVSPPPSPP
PEHHPPPPPI KKMSDMSVSI PPSEKEEQKQ VEQVTFPESS WPPPPPPMEE STELMFEEQD
ELDFPPPPPS FIHEPMSEIS DDFHEESCEE VSIKLLSTNV SDMDSSPEQD SERHTILPKR
IVQNSVEVRQ QDKSSDSVSE FLEDQAEIEN TNVASTIISS HLPDKNLHEK ETLVSTSIPL
APPLPVEEQS TINFRKQLSF VDKDNRSKEL LCRHKSTPIP KEDANIPLVT PSLLQMVRLR
SVNVGEDQVN NDSKPSTEPT TNEDHSISSQ VTPQKPIRRS LTLKSNSPAK SSSASSAVPS
MCLQEAIRMK TAAMSCSGVP AMLNLRSSSG SSATSPVPSP KSPDGCDLLM SPASTASFIF
SKSTKRVVIE TPTSPDVQAS LKQSLAAEIM QVSDQAKTMI TNGTKKPIKV PPPVAKKPVH
GSNPPNKMEN ATQDKTEILT NKQIMRVDVN GQSDQVHPAG QRAQSLGNQE QASKEAFAMN
MSICA
