K1755_MOUSE
ID K1755_MOUSE Reviewed; 1187 AA.
AC Q8BWG4; A2AC61; B2RQJ6;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-FEB-2008, sequence version 2.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=Uncharacterized protein KIAA1755 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C57BL/6J; TISSUE=Kidney;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
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DR EMBL; AK052605; BAC35060.1; -; mRNA.
DR EMBL; AL663063; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC137959; AAI37960.1; -; mRNA.
DR EMBL; BC137960; AAI37961.1; -; mRNA.
DR CCDS; CCDS16986.1; -.
DR RefSeq; NP_001124493.1; NM_001131021.2.
DR RefSeq; NP_808325.2; NM_177657.5.
DR AlphaFoldDB; Q8BWG4; -.
DR SMR; Q8BWG4; -.
DR STRING; 10090.ENSMUSP00000040546; -.
DR iPTMnet; Q8BWG4; -.
DR PhosphoSitePlus; Q8BWG4; -.
DR PaxDb; Q8BWG4; -.
DR PRIDE; Q8BWG4; -.
DR Antibodypedia; 55264; 11 antibodies from 7 providers.
DR DNASU; 228846; -.
DR Ensembl; ENSMUST00000046944; ENSMUSP00000040546; ENSMUSG00000037813.
DR GeneID; 228846; -.
DR KEGG; mmu:228846; -.
DR UCSC; uc008npv.3; mouse.
DR MGI; MGI:3606579; D630003M21Rik.
DR VEuPathDB; HostDB:ENSMUSG00000037813; -.
DR eggNOG; KOG4240; Eukaryota.
DR GeneTree; ENSGT00940000161174; -.
DR InParanoid; Q8BWG4; -.
DR OMA; HLHHFCK; -.
DR OrthoDB; 112611at2759; -.
DR PhylomeDB; Q8BWG4; -.
DR TreeFam; TF334329; -.
DR BioGRID-ORCS; 228846; 5 hits in 71 CRISPR screens.
DR PRO; PR:Q8BWG4; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q8BWG4; protein.
DR Bgee; ENSMUSG00000037813; Expressed in adrenal gland and 49 other tissues.
DR ExpressionAtlas; Q8BWG4; baseline and differential.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..1187
FT /note="Uncharacterized protein KIAA1755 homolog"
FT /id="PRO_0000317285"
FT REGION 302..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 419..451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 511..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1095..1134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1148..1187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..378
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1156..1187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 1067
FT /note="A -> G (in Ref. 1; BAC35060)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1187 AA; 129087 MW; DA236C7DA7A9B572 CRC64;
MDPSALDMAI QHALAGLYPP FEATAPTVLG QVFRLLDSDF RGDGLSFLLD FLIPAKRLCE
QVREAACALY THCLFLHEGW PLCLRDEVVV HLAPLNPLLL RQGDFYLQVE SWEEQSVHMT
LKCLSSDLRE VDKKPIPESS YSLIFTPEWL EAINNDFEGR PLHNCLVASE NGITPVPWTK
ITSPEFVDDR PPIVKVPSSD GDSCPLEDLH LSRPQEPYQA GDLGGKGSVA QIWDKGKGKL
SGDKYPGLIK VEPARSGQLA FRTDSEASQS LEGDYVALLG FPQEYRGASP DSEVVTLSVD
IQKSQETRPR TKGAPLLGKT LPLSGPAGAP PLGRWACERP AGSGEKPCSG GSRRKARHKA
SGHTAVRQPQ QPHTSVPEKL PDCTSGLVED TEEEPAASEM QKPVGMPEAM VRLRPGPRQA
FSPLLSSAGP GSPAAETKTE ETTLGHGRAS KPEDCLNKNA SFHGSPAPGL QFSFLKEQRV
PHVTPEKALL QHARPRKALC PLYSLQPCEA KAPGKDGTTL PTTSGSGPLS GEPPGFRRDS
AGPPGGGLRL EECSRTKPRI ETLGVKLLQS GIACLPGGRD KVGRPLLLVS TAEDAWEAPW
CTTSEVAELL SYLCSVPRLE DKAKGLLVVI DARKGTQRPG LVSALQGIQA LAPASVSKVL
LLGEKASIPQ LSVLPAQVEV LTSLKALRNH VDPSQLPEAL EGPFPYHHSE WVQFFQKLDP
FLTDLRQASS LLQASIQEFE KGEPPGGVQE ATRCLSKSKE LMETVLRDPG LLALQREGGT
TLASLQQEAS GLNANPDVRS HLTEAAALYN LVDGQLHDLV TASNQLLRRL ELRVRLGHLE
TAIHQVSDWM AGEGSQSLQA LAPVHVCAET VEKVHAEFED FFLQVAAQYR QGLDLSKQAA
QLGAAEEGAG EMGLPDLAAF ASTQQAFQAR LTHFYMAAER QRTDLETLLH LHRFRRKMSR
FHMDCQNLLT QLSLGKAVKA SPGDQLHLRL HCYLKRLASE FQTEKLLAMK LQVASLSRPG
LGQEVWEEAQ ERHQEIQSLL RKALAYCPCP EVPATQVALI DRSRPVAKGQ GLPREVGSKW
DRSLQDSLAV DHVFKSQRTP QGEQSRNMWA GLLSPEPGQS GDTEEVRGTP KLPDPTLERL
LASLFSWPHL PKQSKASRPT GGSFSSEGTG SQTSLEDSPH TSPPASL
