ID   50511_ASFM2             Reviewed;         542 AA.
AC   Q65259;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=Protein MGF 505-11L;
GN   OrderedLocusNames=Mal-157;
OS   African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10500;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8409937; DOI=10.1099/0022-1317-74-10-2125;
RA   Vydelingum S., Baylis S.A., Bristow C., Smith G.L., Dixon L.K.;
RT   "Duplicated genes within the variable right end of the genome of a
RT   pathogenic isolate of African swine fever virus.";
RL   J. Gen. Virol. 74:2125-2130(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8021596; DOI=10.1099/0022-1317-75-7-1655;
RA   Dixon L.K., Twigg S.R.F., Baylis S.A., Vydelingum S., Bristow C.,
RA   Hammond J.M., Smith G.L.;
RT   "Nucleotide sequence of a 55 kbp region from the right end of the genome of
RT   a pathogenic African swine fever virus isolate (Malawi LIL20/1).";
RL   J. Gen. Virol. 75:1655-1684(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC       efficient virus replication in macrophages.
CC       {ECO:0000250|UniProtKB:Q65208}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the asfivirus MGF 505 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X71982; CAA50856.1; -; Genomic_DNA.
DR   EMBL; AY261361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   SMR; Q65259; -.
DR   Proteomes; UP000000860; Genome.
DR   InterPro; IPR004858; MGF_505.
DR   Pfam; PF03158; DUF249; 1.
PE   3: Inferred from homology;
KW   Early protein.
FT   CHAIN           1..542
FT                   /note="Protein MGF 505-11L"
FT                   /id="PRO_0000373356"
SQ   SEQUENCE   542 AA;  63509 MW;  E3BA5AF8A3260161 CRC64;
     MFSLQKKALQ HIYMTPENAS ELSKDLLQHL GLYWNGPIIK MDTVVHLHNK IFSNRSVLKY
     ALAKQANITI IETLVLWVEP EYALAQALKH NRKDVLECIF SYHLTTPKYH HIMHLTSSQE
     LFEFFHLFIC KSKNYHARME CLLYAATLYN FQNILEKNRE YIIRHSIGNP LFAIACKERH
     INLIAWFVTA GVLDTYDDST LFNTAFKLGD YSLLEVACDL PITYPDYLII SMMQTAIQKN
     YFRFFKKLLT HFSIYRPIII TDAAYYDRRK ILLLLLNQNI FNNFTILCAL SAAIKGHASK
     KTLNLLINRL DSQMTVIDSV YYSIIKYNNI DCIPLLMHIK TFRMETLISI AVHGDNIDII
     AACKAFLPKD TLYHLVLKMA IILRNHKLFK LYTEKEHPMY IFTILKAIIS DFINYTVFQA
     LAIEYLCKFH QEKQLPIVPL LMVLAEHNYI TKFKKTCYAA NMSDQKVKRA LIKCLFIATQ
     KNYCQIFKYC FGSLLKVLSK HEQEKFFNSV VFAKKLASYY DHQNMIQLID SLIERFRYLL
     KA