ID   K1PF_RHOCA              Reviewed;         316 AA.
AC   P23386;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=1-phosphofructokinase {ECO:0000250|UniProtKB:P0AEW9};
DE            EC=2.7.1.56 {ECO:0000250|UniProtKB:P0AEW9};
DE   AltName: Full=Fructose 1-phosphate kinase {ECO:0000303|PubMed:1850730, ECO:0000303|PubMed:2254279};
DE            Short=Fru1PK {ECO:0000250|UniProtKB:P0AEW9};
GN   Name=fruK {ECO:0000303|PubMed:1850730, ECO:0000303|PubMed:2254279};
OS   Rhodobacter capsulatus (Rhodopseudomonas capsulata).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Rhodobacter.
OX   NCBI_TaxID=1061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DSM 938 / 37b4;
RX   PubMed=1850730; DOI=10.1128/jb.173.10.3117-3127.1991;
RA   Wu L.-F., Reizer A., Reizer J., Cai B., Tomich J.M., Saier M.H. Jr.;
RT   "Nucleotide sequence of the Rhodobacter capsulatus fruK gene, which encodes
RT   fructose-1-phosphate kinase: evidence for a kinase superfamily including
RT   both phosphofructokinases of Escherichia coli.";
RL   J. Bacteriol. 173:3117-3127(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 288-316.
RC   STRAIN=DSM 938 / 37b4;
RX   PubMed=2254279; DOI=10.1128/jb.172.12.7167-7178.1990;
RA   Wu L.-F., Saier M.H. Jr.;
RT   "Nucleotide sequence of the fruA gene, encoding the fructose permease of
RT   the Rhodobacter capsulatus phosphotransferase system, and analyses of the
RT   deduced protein sequence.";
RL   J. Bacteriol. 172:7167-7178(1990).
CC   -!- FUNCTION: Catalyzes the ATP-dependent phosphorylation of fructose-l-
CC       phosphate to fructose-l,6-bisphosphate. {ECO:0000250|UniProtKB:P0AEW9}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + beta-D-fructose 1-phosphate = ADP + beta-D-fructose 1,6-
CC         bisphosphate + H(+); Xref=Rhea:RHEA:14213, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:32966, ChEBI:CHEBI:138881,
CC         ChEBI:CHEBI:456216; EC=2.7.1.56;
CC         Evidence={ECO:0000250|UniProtKB:P0AEW9};
CC   -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC       {ECO:0000305}.
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DR   EMBL; X53150; CAA37302.1; -; Genomic_DNA.
DR   PIR; A39407; A39407.
DR   AlphaFoldDB; P23386; -.
DR   SMR; P23386; -.
DR   OMA; GETRSNI; -.
DR   GO; GO:0008662; F:1-phosphofructokinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   CDD; cd01164; FruK_PfkB_like; 1.
DR   Gene3D; 3.40.1190.20; -; 1.
DR   InterPro; IPR022463; 1-PFruKinase.
DR   InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR   InterPro; IPR011611; PfkB_dom.
DR   InterPro; IPR029056; Ribokinase-like.
DR   InterPro; IPR017583; Tagatose/fructose_Pkinase.
DR   Pfam; PF00294; PfkB; 1.
DR   PIRSF; PIRSF000535; 1PFK/6PFK/LacC; 1.
DR   SUPFAM; SSF53613; SSF53613; 1.
DR   TIGRFAMs; TIGR03168; 1-PFK; 1.
DR   TIGRFAMs; TIGR03828; pfkB; 1.
DR   PROSITE; PS00583; PFKB_KINASES_1; 1.
DR   PROSITE; PS00584; PFKB_KINASES_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Kinase; Nucleotide-binding; Transferase.
FT   CHAIN           1..316
FT                   /note="1-phosphofructokinase"
FT                   /id="PRO_0000080081"
FT   ACT_SITE        257
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250|UniProtKB:P0A9J6"
FT   BINDING         225..230
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250|UniProtKB:P0A9J6"
FT   BINDING         256..257
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250|UniProtKB:P0A9J6"
SQ   SEQUENCE   316 AA;  31232 MW;  0E860107D46FD4B9 CRC64;
     MTLRIATVSL NSAVDQTVTV PGFTADAVNR VAASRIDAGG KGVNVASFLA HVGHGVAVTG
     LLGAENAALF ARHFAATGLV DACQRLPGAT RTNVKIVDPL QDQVTDLNFP GIAAGPADLD
     AVAATLTELL AQGLDWVALC GSLPAGIGAE AYAELAALAR KGGARVALDT SGPALGLALA
     ARPDIVKPNV AELGAHLGRT LTGLESVREA ARDLAASGVG LVAVSMGAGG AVLVRGAEAV
     LAIPPATPIA STVGAGDAMV AGLIHAATLG LDLAETARLA TAFSLGALGE IGPHLPPPER
     LAALARTVTV KTLPPV